Alkaline hydrolysis

From Conservapedia

Jump to: navigation, search

Alkaline hydrolysis is the cleavage of covalent chemical bonds by a high pH.

At high pH, RNA molecules have 2' hydroxyls that attack the 3' phosphodiester bond and degrade the RNA polymer to monoribonucleotides.

DNA lacks 2' hydroxyl groups and cannot be hydrolyzed at high pH.

Personal tools