Chopra left the White House in early 2012, to run for office in Virginia. On July 12, 2012, Chopra formally announced he was running in 2013 for Lieutenant Governor for the Commonwealth of Virginia. He was expecting to run against Jeannemarie Devolites Davis, the wife of former Congressman Thomas M. Davis. Instead, the Republicans selected a more conservative candidate, E.W. Jackson, and in turn the June 11 Democratic primary seleced centrist Sen. Ralph Northam M.D. to run against Jackson. The vote was 78,337 (54.24%) for Northam and 66,098 (45.76%) for Chopra. Northam drew support from the Tidewater area, but Chopra did not gain the support he expected from Northern Virginia, in part due to his controversial Wikipedia ties.
- O'Keefe, Ed. "Aneesh Chopra leaving the White House, likely to run for Virginia lieutenant governor", January 27, 2012. Retrieved on September 16, 2012.
- Kumar, Anita (July 12, 2012). Aneesh Chopra to run for Virginia lieutenant governor. The Washington Post. Retrieved on September 16, 2012.
- Unofficial Results - Primary Election - June 11, 2013. Retrieved on July 13, 2013.