Obesity and Alzheimer's disease
See also: Obesity and Alzheimers disease
In 2005, WebMD published:
|“|| People with diabetes are at particularly high risk of Alzheimer's disease. But now there's strong evidence that people with high insulin levels -- long before they get diabetes -- already are on the road to Alzheimer's disease.
As the body becomes more and more overweight, it becomes more and more resistant to the blood-sugar-lowering effects of insulin. To counter this insulin resistance, the body keeps making more insulin...
Insulin Triggers Amyloid Buildup
High insulin levels are known to cause blood vessels to become inflamed....
One dangerous effect of this insulin-caused brain inflammation is increased brain levels of beta-amyloid. Beta-amyloid is the twisted protein that's the main ingredient in the sticky plaques that clog the brains of people with Alzheimer's disease.
"What was striking was the magnitude of the effect," Craft tells WebMD. "Inflammation can be a result of amyloid elevations but can also create an environment in which amyloid is made more readily. Inflammation can be both the result and cause of amyloid production."
A 2009 health report on a medical study indicated:
|“|| They compared the brain scan of 94 people in their 70s who were obese & overweight. They found that the obese had lost tissue in the frontal & temporal lobes areas critical for planning & memory. Declines were also seen in areas used for attention & executive functions, long term memory & movement
A neurologist Professor Paul Thompson said, “That's a big loss of tissue and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer's and other diseases that attack the brain. But you can greatly reduce your risk for Alzheimer's if you can eat healthily and keep your weight under control.”M
Health effects of Alzheimer's disease
Alzheimer's disease is "characterised by loss of neurons and synapses in the cerebral cortex and certain subcortical regions. This loss results in gross atrophy of the affected regions, including degeneration in the temporal lobe and parietal lobe, and parts of the frontal cortex and cingulate gyrus. Some of the primary symptoms of Alzheimer's disease are: memory problems, mood swings, emotional outbursts, brain stem damage which impairs function in the heart, lungs plus causes disruption of various other bodily processes.
An abstract of the medical study entitled Measures to Assess the Noncognitive Symptoms of Dementia in the Primary Care Setting by Brent P. Forester, M.D. and Thomas E. Oxman, M.D. inidcated "Noncognitive symptoms associated with Alzheimer's disease and related dementias include psychosis, mood disturbances, personality changes, agitation, aggression, pacing, wandering, altered sexual behavior, changed sleep patterns, and appetite disturbances. These noncognitive symptoms of dementia are common, disabling to both the patient and the caregiver, and costly."
According to the Center for Neuro Skills:
|“||Kolb & Wishaw (1990) have identified eight principle symptoms of temporal lobe damage: 1) disturbance of auditory sensation and perception, 2) disturbance of selective attention of auditory and visual input, 3) disorders of visual perception, 4) impaired organization and categorization of verbal material, 5) disturbance of language comprehension, 6) impaired long-term memory, 7) altered personality and affective behavior, 8) altered sexual behavior.||”|
Obesity, Alzheimer's disease and prevention
See also: Alzheimer's disease and prevention
Weili Xu, a researcher at the Karolinska Institute in Stockholm, declared: "Our results contribute to the growing evidence that controlling body weight or losing weight in middle age could reduce your risk of dementia".
For more information please see: Alzheimer's disease and prevention
- Atheism and obesity
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- Homosexuality and obesity
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- Atheism and health
- Homosexuality and health
- Exploring the Links between Obesity and Alzheimer’s Disease
- Meta-analysis of Alzheimer's disease risk with obesity, diabetes, and related disorders - Biol Psychiatry. 2010 Mar 15;67(6):505-12. Epub 2009 Apr 9. Profenno LA, Porsteinsson AP, Faraone SV.
- Scientists Discover Mechanism Tying Obesity To Alzheimer's Disease = ScienceNews, 2005
- Obesity in Middle Age May Increase Risk of Dementia
Weight loss resources and tips
- Obesity and an F grade in fat - A need for faith in God
- Weight-loss goals: 10 tips for success by Mayo Clinic
- Zone Diet
- Mediterranean diet by Mayo Clinic
- Glycemic index diet: Losing weight with blood sugar control by Mayo Clinic
- Lose weight fast: How to do it safely by WebMD
- Weight loss: Cardio Exercise vs. Weight Training - Vanderbilt University, Health Psychology Home Page
Documentary on weight loss:
- IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation - Lipids Health Dis. 2009 Mar 2;8:7,Ngondi JL, Etoundi BC, Nyangono CB, Mbofung CM, Oben JE.
- The effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in Cameroon - Lipids Health Dis. 2005; 4: 12, Judith L Ngondi, Julius E Oben, Samuel R Minka
- IRVINGIA GABONENSIS - WebMD
- ↑ Obesity and Alzheimer's: High Insulin Levels Linked to Alzheimer's
- ↑ Obese people are more at risk of Alzheimer’s
- ↑ http://www.news-medical.net/health/Neurodegeneration-in-Alzheimers-and-Parkinsons.aspx
- ↑ http://www.dementiacarecentral.com/node/559
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419385/
- ↑ http://www.neuroskills.com/tbi/btemporl.shtml
- ↑ Obesity in Middle Age May Increase Risk of Dementia