Have there been cases of overdose? As many as with aspirin?
Surely not from drinking 100 cups of coffee: the water overload would kill you before the caffeine overdose. Maximum "dose" of water is 2 gallons (128 oz.), and you'd have to drink 800 oz. of coffee to get a caffeine overdose.
- well actually, the diuretic effect of the caffeine and its metabolites would prevent water poisoning - the fact of the matter is that you CAN overdose on caffeine. Wisdom89 15:59, 30 August 2007 (EDT)