Jacob had a total of twelve sons born to him, in a definite order. That order would later be significant in God's design for the breastplate of judgment for the high priests of Israel.
In addition to these, Jacob had a daughter, Dinah, by his wife Leah. Her birth occurred about 2254 AM (1750 BC. Genesis 30:21
The sons went on to found the Twelve Tribes of Israel except that Levi was not included in that list and in place of Joseph were his two sons, Manasseh and Ephraim, thereby keeping a full twelve.
In Christian thought, it has been noted that the meanings of the names of the twelve sons prefigure Jesus Christ—son of God, Who has heard the cries of man, seeks to facilitate a joining of man and God, is worthy of praise, is the righteous Judge of the world, assists man in the struggle against sin, can call a troop or company of angels, is the Source of happiness (for without Him no man can be content, while with Him any man can be content), will reward us for our service (though His salvation is a free gift), shall add to our joys, and sits at the right hand of the Father.