Difference between revisions of "Endogenous retrovirus"

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ERV's are usually species specific, insert almost randomly in the host genome, and the error or mutation that inactivated the gene is random. Because of these factors if two organisms share the same ERV, in the same location with the same inactivation mutations then they must share them due to common inheritance and not two separate infections. This fact has allowed for analysis of shared ERV insertions across species in order to construct [[phylogenetic trees]].
 
ERV's are usually species specific, insert almost randomly in the host genome, and the error or mutation that inactivated the gene is random. Because of these factors if two organisms share the same ERV, in the same location with the same inactivation mutations then they must share them due to common inheritance and not two separate infections. This fact has allowed for analysis of shared ERV insertions across species in order to construct [[phylogenetic trees]].
  
Creationists assert that endogenous retroviruses are invalid as proofs for the [[theory of evolution]].<ref>http://www.trueorigin.org/theobald1e.asp</ref><ref>http://www.answersingenesis.org/articles/am/v1/n2/were-retroviruses-created-good</ref><ref>http://www.answersingenesis.org/docs2006/1219herv.asp</ref>
 
  
 
==See also==
 
==See also==

Revision as of 23:18, 3 April 2007

A diagram showing the phylogenetic tree of primates constructed from shared ERV insertions along with when these insertions took place.

An Endogenous retrovirus (ERV) is genetic insertion in an organism's genome from an inactivated retrovirus. A retrovirus stores its genetic information in RNA and must reverse transcribe it into DNA before insertion into the host's genome. This process is prone to error and sometimes the errors will inactivate the gene. When these inactivate genes are inserted in the germ line of the host all its descendants will also have the inactivated insertion. Human endogenous retroviruses (HERV) have been linked to several autoimmune diseases such as multiple sclerosis.

ERV's are usually species specific, insert almost randomly in the host genome, and the error or mutation that inactivated the gene is random. Because of these factors if two organisms share the same ERV, in the same location with the same inactivation mutations then they must share them due to common inheritance and not two separate infections. This fact has allowed for analysis of shared ERV insertions across species in order to construct phylogenetic trees.


See also

Pseudogene

References