Down syndrome - Revision history

Tg97 at 03:03, May 14, 2018

2018-05-14T03:03:03Z

DavidB4-bot: /* Treatment */Spelling, Grammar, and General Cleanup

2018-02-08T20:00:30Z

‎Treatment: Spelling, Grammar, and General Cleanup

MattF at 00:05, January 5, 2018

2018-01-05T00:05:10Z

JoeyJ at 19:54, March 25, 2017

2017-03-25T19:54:01Z

DavidB4-bot: /* top */clean up & uniformity

2016-07-13T11:47:14Z

‎top: clean up & uniformity

DavidB4-bot: /* top */Spelling, Grammar, and General Cleanup, typos fixed: inpired → inspired

2016-07-11T13:30:38Z

‎top: Spelling, Grammar, and General Cleanup, typos fixed: inpired → inspired

OconnorM at 15:37, August 28, 2013

2013-08-28T15:37:35Z

OconnorM at 15:35, August 28, 2013

2013-08-28T15:35:59Z

Gregkochuconn: removing the ambiguous word "Low". If this was supposed to say "Low [something]" feel free to readd it.

2011-06-04T02:35:13Z

removing the ambiguous word "Low". If this was supposed to say "Low [something]" feel free to readd it.

Sunda62: DS and cancer - FACTS, based on SCIENCE

2009-06-10T17:12:46Z

DS and cancer - FACTS, based on SCIENCE

← Older revision		Revision as of 03:03, May 14, 2018
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−	'''Down syndrome''' (also written as '''Down's syndrome''', technical name '''Trisomy 21'''<ref>http://www.ds-health.com/trisomy.htm</ref>) is a genetic disorder caused by an extra copy of [[chromosome]] 21. IT is the most common syndrome caused by chromosomal abnormalities in human beings. The greatest risk factor for having a child with Down syndrome is increased maternal (and, to a lesser extent, paternal) age.	+	'''Down syndrome''' (also written as '''Down's syndrome''', technical name '''Trisomy 21'''<ref>http://www.ds-health.com/trisomy.htm</ref>) is a genetic disorder caused by an extra copy of [[chromosome]] 21. It is the most common syndrome caused by chromosomal abnormalities in human beings. The greatest risk factor for having a child with Down syndrome is increased maternal (and, to a lesser extent, paternal) age.

	== History ==		== History ==

@@ Line 27: / Line 27: @@
 == Treatment ==
-On July 13, 2013, researchers at University of Massachusetts--Worcester took cells from Down syndrome people and were able to turn off the extra chromosomes that cause the disorder, though available treatment is still a long way from now. <ref>https://www.theguardian.com/science/2013/jul/17/downs-syndrome-cells-fixed-chromosome-therapy</ref>
+On July 13, 2013, researchers at University of Massachusetts—Worcester took cells from Down syndrome people and were able to turn off the extra chromosomes that cause the disorder, though available treatment is still a long way from now.<ref>https://www.theguardian.com/science/2013/jul/17/downs-syndrome-cells-fixed-chromosome-therapy</ref>
 ==References==

← Older revision		Revision as of 00:05, January 5, 2018
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	The greatest risk factor in is increased maternal age, the majority of children with Down syndrome are born to mothers under the age of 35, because the vast majority of children as a whole are born to younger mothers.		The greatest risk factor in is increased maternal age, the majority of children with Down syndrome are born to mothers under the age of 35, because the vast majority of children as a whole are born to younger mothers.
		+
		+	== Treatment ==
		+	On July 13, 2013, researchers at University of Massachusetts--Worcester took cells from Down syndrome people and were able to turn off the extra chromosomes that cause the disorder, though available treatment is still a long way from now. <ref>https://www.theguardian.com/science/2013/jul/17/downs-syndrome-cells-fixed-chromosome-therapy</ref>

	==References==		==References==

@@ Line 1: / Line 1: @@
 '''Down syndrome''' (also written as '''Down's syndrome''', technical name '''Trisomy 21'''<ref>http://www.ds-health.com/trisomy.htm</ref>) is a genetic disorder caused by an extra copy of [[chromosome]] 21. IT is the most common syndrome caused by chromosomal abnormalities in human beings. The greatest risk factor for having a child with Down syndrome is increased maternal (and, to a lesser extent, paternal) age.
 The name comes from [[British]] [[physician]] [[John Langdom Down]], who described the syndrome in his [[1862]] paper, "Observations on an Ethnic Classification of Idiots". Down conjectured that the syndrome was a "degeneracy" of [[caucasians]] to [[mongols]] (the [[mongolian]] race was  one of the five racial classifications commonly used at the time), and the term '''mongolism''' was inspired by his paper.  Currently, the terms "mongolism" and "mongoloid" are considered offensive. <!-- reference:
 http://www.neonatology.org/classics/down.html, original paper //-->
 The most important medical aspect of Down syndrome is [[mental retardation]]. Individuals with Down syndrome have mild to severe mental retardation. It is impossible to reliably predict what the eventual level of function of a child with Down syndrome will be.

@@ Line 20: / Line 20: @@
 * Early onset [[Alzheimer's disease]]
-People with Down Syndrome have significantly lesser rates of cancer than other people <ref>[http://www.downsyn.com/cancer.php]</ref>; in fact, recent studies about the correlation of Down Syndrome and cancer may even provide a cure for cancer <ref>http://www.nature.com/news/2009/090520/full/news.2009.493.html</ref>.
+People with Down Syndrome have significantly lesser rates of cancer than other people;<ref>[http://www.downsyn.com/cancer.php]</ref> in fact, recent studies about the correlation of Down Syndrome and cancer may even provide a cure for cancer.<ref>http://www.nature.com/news/2009/090520/full/news.2009.493.html</ref>
 The greatest risk factor in is increased maternal age, the majority of children with Down syndrome are born to mothers under the age of 35, because the vast majority of children as a whole are born to younger mothers.

@@ Line 12: / Line 12: @@
 * Weak muscle tone
 * Enlarged, protruding [[tongue]]
-* [[Congenital heart defect]]
+* [[Congenital heart defect]]- Atrioventricular septal defects
 * [[Gastroesophageal reflux disease]]
 * [[Otitis]] and hearing deficits

← Older revision		Revision as of 15:35, August 28, 2013
Line 1:		Line 1:
−	'''Down syndrome''' (also written as '''Down's syndrome''', technical name '''Trisomy 21'''<ref>http://www.ds-health.com/trisomy.htm</ref>) is a genetic disorder caused by an extra copy of [[chromosome]] 21. The greatest risk factor for having a child with Down syndrome is increased maternal (and, to a lesser extent, paternal) age.	+	'''Down syndrome''' (also written as '''Down's syndrome''', technical name '''Trisomy 21'''<ref>http://www.ds-health.com/trisomy.htm</ref>) is a genetic disorder caused by an extra copy of [[chromosome]] 21. IT is the most common syndrome caused by chromosomal abnormalities in human beings. The greatest risk factor for having a child with Down syndrome is increased maternal (and, to a lesser extent, paternal) age.

	The name comes from [[British]] [[physician]] [[John Langdom Down]], who described the syndrome in his [[1862]] paper, "Observations on an Ethnic Classification of Idiots". Down conjectured that the syndrome was a "degeneracy" of [[caucasians]] to [[mongols]] (the [[mongolian]] race was one of the five racial classifications commonly used at the time), and the term '''mongolism''' was inpired by his paper. Currently, the terms "mongolism" and "mongoloid" are considered offensive. <!-- reference:		The name comes from [[British]] [[physician]] [[John Langdom Down]], who described the syndrome in his [[1862]] paper, "Observations on an Ethnic Classification of Idiots". Down conjectured that the syndrome was a "degeneracy" of [[caucasians]] to [[mongols]] (the [[mongolian]] race was one of the five racial classifications commonly used at the time), and the term '''mongolism''' was inpired by his paper. Currently, the terms "mongolism" and "mongoloid" are considered offensive. <!-- reference:

@@ Line 17: / Line 17: @@
 * [[Sleep apnea]]
 * [[Thyroid]] hormone problems
-* [[Leukemia]]
+* Increased risk of [[Leukemia]], but reduced risk of other forms of [[cancer]]
 * Early onset [[Alzheimer's disease]]
-There is some evidence that people with Down syndrome are at higher risk than others of developing leukemia, but lower risk of developing other cancers<ref>[http://www.downsyn.com/cancer.php]</ref>.
+People with Down Syndrome have significantly lesser rates of cancer than other people <ref>[http://www.downsyn.com/cancer.php]</ref>; in fact, recent studies about the correlation of Down Syndrome and cancer may even provide a cure for cancer <ref>http://www.nature.com/news/2009/090520/full/news.2009.493.html</ref>.
 The greatest risk factor in is increased maternal age, the majority of children with Down syndrome are born to mothers under the age of 35, because the vast majority of children as a whole are born to younger mothers.