In June of 2004, the journal ''Nursing Clinics of North America'' reported concerning '''homosexuality and anal cancer''':{{Homosexuality and health}}{{cquote|One of the more pressing issues for [[homosexuality|gay men]] is anal carcinoma. Several recent studies have indicated the rate of anal dysplasia to be increasing in men with and without [[HIV]]. Ninety percent of men with HIV have the [[Human Papiloma VirusHPV|human papiloma virus]] ([[HPV]]), while 65% of men without HIV have HPV. HPV type 16 is the most troublesome for developing cancer and is found in a significant portion of gay men.
Another risk factor for developing anal cancer is the use of recreational drugs anally...Inserting "crystal [[methamphetamine |meth]]" or ecstasy in the rectum can lead to higher rates of anal dylpasia.<ref>[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=AbstractPlus&list_uids=15159188 Nursing Clinics of North America North Am. 2004 Jun;39(2):404]</ref>}}