Difference between revisions of "Felisa Wolfe-Simon"

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In 2012, two reports refuting the most significant aspects of the original results were published in the same journal in which the original findings had been previously published.<ref> Erb, T. J.; Kiefer, P.; Hattendorf, B.; Gunther, D.; Vorholt, J. A. (2012). "GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism". Science. 337 (6093): 467–470. doi:10.1126/science.1218455</ref><ref>Reaves, M. L.; Sinha, S.; Rabinowitz, J. D.; Kruglyak, L.; Redfield, R. J. (2012). "Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells". Science. 337 (6093): 470–473. doi:10.1126/science.1219861.</ref>
 
In 2012, two reports refuting the most significant aspects of the original results were published in the same journal in which the original findings had been previously published.<ref> Erb, T. J.; Kiefer, P.; Hattendorf, B.; Gunther, D.; Vorholt, J. A. (2012). "GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism". Science. 337 (6093): 467–470. doi:10.1126/science.1218455</ref><ref>Reaves, M. L.; Sinha, S.; Rabinowitz, J. D.; Kruglyak, L.; Redfield, R. J. (2012). "Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells". Science. 337 (6093): 470–473. doi:10.1126/science.1219861.</ref>
  
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As of 2014, Wolfe-Simon was working at Lawrence Berkeley National Laboratory in California in relative obscurity.<ref>http://www.the-scientist.com/?articles.view/articleNo/41056/title/Setting-the-Record-Straight/</ref>
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As of 2014, Wolfe-Simon was working in relative obscurity at Lawrence Berkeley National Laboratory in Berkeley, California.<ref>http://www.the-scientist.com/?articles.view/articleNo/41056/title/Setting-the-Record-Straight/</ref>
  
 
==Notes==
 
==Notes==

Revision as of 08:02, February 9, 2017

Felisa Wolfe-Simon (b. 1978) is an American microbial geobiologist and biogeochemist. In 2010, Wolfe-Simon led a team that discovered GFAJ-1 ("Give Felisa A Job"), an arsenate-resistant bacterium that they claimed was capable of substituting arsenic for a small percentage of the phosphorus in its DNA, even implying that they were extra-terrestrial in origin. GFAJ-1 was isolated from arsenic-rich Mono Lake in California. Her team used a radioactive arsenate isotope (73-As) and exotic but inconclusive X-ray absorption studies (XAS measurements) at Stanford Synchrotron Radiation Lightsource (SSRL).[1]

These claims received wide publicity at the time in part because of a December 2010 NASA press-release style video in which presentation and because of Wolfe-Simon's gender, youth and charisma, talking in the style of Carl Sagan.[2] Experts soon expressed doubts in her claims but Wolfe-Simon delayed sharing samples of GFAJ-1 for six months. In April 2011, Time magazine named her to their list of 100 most influential people in the world for 2011.[3] Wolfe-Simon last posted on her Twitter account as "ironlisa" in May 2011.[4]

In 2011, University of British Columbia microbiologist Rosie Redfield, obtained a sample of GFAJ-1 from Wolfe-Simon's team and attempted to replicate the results. Redfield used more traditional laboratory techniques and in August 2011 published that she failed to reproduce Wolfe-Simon results.[5]

In 2012, two reports refuting the most significant aspects of the original results were published in the same journal in which the original findings had been previously published.[6][7]

As of 2014, Wolfe-Simon was working in relative obscurity at Lawrence Berkeley National Laboratory in Berkeley, California.[8]

Notes

  1. ↑ http://cen.acs.org/articles/90/i29/Two-Studies-Rebut-Arsenic-Based.html
  2. ↑ http://science.sciencemag.org/content/sci/early/2010/12/01/science.1197258.full.pdf (Online. Finally published in print in June 2011)
  3. ↑ http://content.time.com/time/specials/packages/article/0,28804,2066367_2066369_2066250,00.html
  4. ↑ https://twitter.com/ironlisa
  5. ↑ http://www.nature.com/news/2011/110809/full/news.2011.469.html
  6. ↑ Erb, T. J.; Kiefer, P.; Hattendorf, B.; Gunther, D.; Vorholt, J. A. (2012). "GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism". Science. 337 (6093): 467–470. doi:10.1126/science.1218455
  7. ↑ Reaves, M. L.; Sinha, S.; Rabinowitz, J. D.; Kruglyak, L.; Redfield, R. J. (2012). "Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells". Science. 337 (6093): 470–473. doi:10.1126/science.1219861.
  8. ↑ http://www.the-scientist.com/?articles.view/articleNo/41056/title/Setting-the-Record-Straight/
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