Changes

[[File:Scrapie prions.jpg|thumbnail|right|An image with PrP immunostained. Note how they move between neurons.]]

[[File:Scrapie prions.jpg|thumbnail|right|An image with PrP immunostained. Note how they move between neurons.]]

'''PrP''', also known as the prion protein or PrPc, is a protein in the brain of most animals. The purpose of it is still debated today. Most scientists believe it has to do with cognition, the [[Circadian rhythm]], or the immune system. Studies show that while they are semi-important in mice, they are not important in [[cow]]s. It is currently unknown if they are important in humans, however it is likely they are due to the existence of [[fatal familial insomnia]]. PrP has prion isoforms called PrPres. Misfolding of PrP is the cause of all [[transmissible spongiform encephalopathy]] diseases. PrPres is highly resistant to [[protease]] digestion, radiation, and temperature. Heating to 2200 degrees Fahrenheit is the only known way to destroy them.  

'''PrP''', also known as the prion protein or PrPc, is a protein in the brain of most animals. The purpose of it is still debated today. Most scientists believe it has to do with cognition, the [[Circadian rhythm]], or the immune system. Studies show that while they are semi-important in mice, they are not important in [[cow]]s. It is currently unknown if they are important in humans, however it is likely they are due to the existence of [[fatal familial insomnia]]. PrP has prion isoforms called PrP^res. Misfolding of PrP is the cause of all [[transmissible spongiform encephalopathy]] diseases. PrP^res is highly resistant to [[protease]] digestion, radiation, and temperature. Heating to 2200 degrees Fahrenheit is the only known way to destroy them.  

==References==

==References==