| − | '''Serotonin''' is a [[neurotransmitter]] found in the human brain. Serotonin is thought to play an important role in a number of physiological and psychological systems, including [[mood]], body temperature, sleep, and sexuality. For example, individuals with below-average levels of serotonin are vulnerable to disorders such as [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s. Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. | + | '''Serotonin''' or '''5-Hydroxytryptamine''' (5-HT) is a biogenic amine [[neurotransmitter]] found in the central nervous system and the gastrointestinal tract. Serotonin is thought to play an important role in a number of physiological and psychological functions, including [[mood]], body temperature, sleep, and sexuality. It is posited that individuals deficient in serotonin are vulnerable to disorders such as [[depression]], [[Obsessive-Compulsive Disorder]], [[anxiety|anxiety disorders]], [[bipolar disorder]], [[irritable bowel syndrome]], ear infections, and [[migraine]]s. Consequently, medications that increase serotonergic activity in the brain are often used to treat these disorders. Examples include antidepressants such as [[monoamine oxidase inhibitors]] (MAOIs), [[Tricyclic anti-depressants]], and [[Selective-Serotonin-Reuptake-Inhibitors]] (SSRIs). |