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'''Insulin''' is a polypeptide hormone synthesized by the beta cells of the Islets of Langerhans within the [[pancreas]]. Insulin stimulates the cells of the body to take up [[glucose]] for cellular metabolism and storage. People who have an insulin deficiency develop the disease [[diabetes]]. Suffers either manifest insulin insensitivity where cells are rendered unresponsive to the hormone, or autoimmune destruction of the beta cells leading to decreased secretion of insulin.  
 
'''Insulin''' is a polypeptide hormone synthesized by the beta cells of the Islets of Langerhans within the [[pancreas]]. Insulin stimulates the cells of the body to take up [[glucose]] for cellular metabolism and storage. People who have an insulin deficiency develop the disease [[diabetes]]. Suffers either manifest insulin insensitivity where cells are rendered unresponsive to the hormone, or autoimmune destruction of the beta cells leading to decreased secretion of insulin.  
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Insulin that is administered in the treatment of diabetes is now made by biotechnology, by growing of human Insulin in a [[genetically modified]], non-disease producing strain of Escherichia coli bacteria.  This method creates an insulin with fewer impurities than the old method of extraction from Bovine (cow) or porcine (pig) pancreas.  
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Insulin that is administered in the treatment of diabetes is now made by biotechnology, by growing of human insulin in a [[genetically modified]], non-disease producing strain of ''Escherichia coli'' bacteria.  This method creates an insulin with fewer impurities than the old method of extraction from bovine (cow) or porcine (pig) pancreas.  
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Insulin was discovered by Canadian Fredrick Banting in 1921, and he would win the [[Nobel Prize]], almost immediately afterwards in 1923.
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Insulin was discovered by Canadian Fredrick Banting in 1921. He and fellow Canadian [[John James Richard McCloud]] would win the [[Nobel Prize]] in Medicine soon afterwards, in 1923.
    
[[category:biology]]
 
[[category:biology]]
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