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'''Horizontal gene transfer''' ('''HGL'''), also called '''Lateral gene transfer''' ('''LGT'''), is the process of transfering genetic material between different species, or across broad taxonomic categories.
==Main mechanisms of gene transfer in prokaryotes==
HGT between distant microbial phyla is mediated by [[bacteriophages]], [[plasmids]], [[transposons]], and specialized cellular DNA uptake mechanisms. These mechanisms usually categorized with the following commonly used technical terms:
* '''Bacterial transformation''' , the genetic alteration of a cell resulting from the introduction, uptake and expression of foreign genetic material, generally [[DNA]] (see this [http://www.learner.org/channel/courses/biology/archive/animations/hires/a_infect3_h.html animation with audio explanation]). This process is relatively common in certain naturally transformable bacteria, such as the soil bacterium ''Bacillus subtilis''. Transformation is often used as a biotechnology to insert novel genes into bacteria for scientific research experiments, or for industrial or medical applications.
* '''Transduction''', the process in which bacterial DNA is moved from one bacterium to another by a bacterial virus (a bacteriophage, commonly called a phage).
* '''Bacterial conjugation''' ( or mating), a process in which a living bacterial cell transfers genetic material through direct cell-to-cell contact (see the animation [http://www.blackwellpublishing.com/trun/artwork/Animations/conjugation/conjugation.html conjugation in ''Escherichia coli'']).
==Main mechanisms of gene transfer in eukaryotes==
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