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first observed by Anton van Leeuwenhoek in the 17th century, but he did not make the connection to disease
Microorganism are living [[organism]]s that are too small to see with the naked eye.<ref>Wile, Dr. Jay L. ''Exploring Creation With Biology''. Apologia
Educational Ministries, Inc. 1998</ref>
Educational Ministries, Inc. 1998</ref> They were first observed by Anton van Leeuwenhoek in the 17th century, but he did not make the connection to disease. That had to wait for Pasteur's [[germ theory of disease]] 200 years later.