The most important medical aspect of Down syndrome is [[mental retardation]]. Individuals with Down syndrome have mild to severe mental retardation (but the cases of extreme mental retardation are usually in those that were abandoned by their unloving parents). | The most important medical aspect of Down syndrome is [[mental retardation]]. Individuals with Down syndrome have mild to severe mental retardation (but the cases of extreme mental retardation are usually in those that were abandoned by their unloving parents). |