The effectiveness of a pain relief medicine is always contrasted with the effectiveness of a placebo. The question is not how well it relieves pain, but how much better is it than a placebo?
==Example of Drug vs Placebo in Headache Pain Management==
{{QuoteBox2|||quote=Two hours after treatment of an in-progress moderate or severe headache, 49% of patients given 100 mg of sumatriptan reported no or mild pain, a significantly greater response rate than the 38% among the placebo group. At 4 hours, the response rate was 64% with sumatriptan and 45% with placebo.|source=[http://findarticles.com/p/articles/mi_hb4345/is_/ai_n29117915]|}}
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==References==