Difference between revisions of "Point mutation"
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A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel". | A '''point mutation''' is the most limited type of [[mutation]], whereby a single base [[nucleotide]] is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel". | ||
Latest revision as of 15:31, February 4, 2009
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A point mutation is the most limited type of mutation, whereby a single base nucleotide is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair, which is also referred to as an "indel".
The sickle-cell disease is caused by a single point mutation in one allele of the beta hemoglobin gene, whereby a CCT codon is converted into TCT. The TCT then mistakenly encodes the amino acid serine instead of proline.
Point mutations do not add new information to the genome. [1]
- ↑ Purdom, Georgia, Feedback: Evidence of New Genetic Information?, 1st February, 2009 (Answers in Genesis)