Changes

→‎Lack of mechanism: vanadium in tunicates
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# In addition, evolution cannot explain the many complex sex-determining systems. For example, in most mammals, females have two X chromosomes whereas males have an X and Y chromosome, but in birds, many insects, and other organisms, the situation is reversed. In flies, sex is determined the ratio of non-sex chromosomes to X chromosomes (so that males have only one X whereas females have two). It is impossible for evolution to create these new sex-determining systems ''ex nihilo''.
 
# In addition, evolution cannot explain the many complex sex-determining systems. For example, in most mammals, females have two X chromosomes whereas males have an X and Y chromosome, but in birds, many insects, and other organisms, the situation is reversed. In flies, sex is determined the ratio of non-sex chromosomes to X chromosomes (so that males have only one X whereas females have two). It is impossible for evolution to create these new sex-determining systems ''ex nihilo''.
 
#  Several species of fish in the Arctic ocean have chemicals in their blood that essentially act as anti-freeze.  Evolution requires gradual change, leaving no plausible explanation as to how the fish survived before developing this trait.
 
#  Several species of fish in the Arctic ocean have chemicals in their blood that essentially act as anti-freeze.  Evolution requires gradual change, leaving no plausible explanation as to how the fish survived before developing this trait.
 +
# The blood of tunicates such as the sea squirt is based on the rare element [[vanadium]] instead of the abundant [[iron]] used in other vertebrates, which would have required a complete re-tooling of its entire circulatory biochemistry <ref>http://www.earthlife.net/inverts/ascidiacea.html</ref>.
    
===Maladaptation===
 
===Maladaptation===