Difference between revisions of "Hepatitis B vaccine"

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The Hepatitis B vaccine is a recombinant (non-living) vaccine used to prevent infection with the [Hepatitis B virus]. Most school age children, health care workers, and others who might be exposed to infectious bodily fluids are recommended or required to become vaccinated.     
 
The Hepatitis B vaccine is a recombinant (non-living) vaccine used to prevent infection with the [Hepatitis B virus]. Most school age children, health care workers, and others who might be exposed to infectious bodily fluids are recommended or required to become vaccinated.     
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'''Recombinant hepatitis B vaccine and the risk of multiple sclerosis'''
 
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<br>A prospective study<ref>http://www.neurology.org/cgi/content/abstract/63/5/838</ref>
 
  
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Miguel A. Hernán, MD, DrPH, Susan S. Jick, DSc, Michael J. Olek, DO and Hershel Jick, MD
 
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From the Department of Epidemiology (Dr. Hernán), Harvard School of Public Health, Boston; Boston Collaborative Drug Surveillance Program (Drs. Susan S. Jick and Hershel Jick), Boston University, Lexington, MA; and Department of Neurology (Dr. Olek), College of Medicine, University of California, Irvine.
 
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Background: A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations.
 
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Methods: The authors conducted a nested case-control study within the General Practice Research Database (GPRD) in the United Kingdom. ...
 
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Results: The analyses include 163 cases of MS and 1,604 controls. The OR of MS for vaccination within 3 years before the index date compared to no vaccination was 3.1 (95% CI 1.5, 6.3). No increased risk of MS was associated with tetanus and influenza vaccinations.
 
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Conclusions: These findings are consistent with the hypothesis that immunization with the recombinant hepatitis B vaccine is associated with an increased risk of MS, and challenge the idea that the relation between hepatitis B vaccination and risk of MS is well understood.
 
  
 
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'''References:'''  <references/>
 
  
 
[[Category:Vaccines]]
 
[[Category:Vaccines]]
 
[[Category:Medicine]]
 
[[Category:Medicine]]

Revision as of 21:14, April 4, 2007

The Hepatitis B vaccine is a recombinant (non-living) vaccine used to prevent infection with the [Hepatitis B virus]. Most school age children, health care workers, and others who might be exposed to infectious bodily fluids are recommended or required to become vaccinated.


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