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Studies indicate that resistance to ''many'' of the chemical pesticides currently used is increasing in some bedbug populations in many areas of North America.<ref>http://newyorkvsbedbugs.org/2010/01/21/kdr-pyrethroid-resistance-widespread-in-u-s-bed-bug-populations/</ref><ref>http://www.faqs.org/periodicals/201006/2054573271.html</ref>  This Resistance is genetically conferred to subsequent populations which then show resistance to other chemical tools within the same class of chemistry. Thus the problem involves all pyrethroids and is likely only to get worse.<ref>http://termidorpartners.com/store/Downloads/BASF-626-Bed-Bugs-Guide.pdf</ref> According to research at the University of Kentucky College of Agriculture, some of the latest “super bedbugs” can survive for up to 16 days after being directly sprayed with currently used pesticides designed to kill insects immediately.  
 
Studies indicate that resistance to ''many'' of the chemical pesticides currently used is increasing in some bedbug populations in many areas of North America.<ref>http://newyorkvsbedbugs.org/2010/01/21/kdr-pyrethroid-resistance-widespread-in-u-s-bed-bug-populations/</ref><ref>http://www.faqs.org/periodicals/201006/2054573271.html</ref>  This Resistance is genetically conferred to subsequent populations which then show resistance to other chemical tools within the same class of chemistry. Thus the problem involves all pyrethroids and is likely only to get worse.<ref>http://termidorpartners.com/store/Downloads/BASF-626-Bed-Bugs-Guide.pdf</ref> According to research at the University of Kentucky College of Agriculture, some of the latest “super bedbugs” can survive for up to 16 days after being directly sprayed with currently used pesticides designed to kill insects immediately.  
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Bedbugs have a cuticle on the outside of their body that is almost impenetrable to many insecticides used today, therefore the bugs do not pick up the dried residues of such very well.  Bedbugs developed resistance to DDT in the 1950s, and then to its successors such as organophosphates like diazinon and malathion which were being used to clear up remaining infestations.<ref>http://www.earthfiles.com/news.php?ID=1768&category=Environment</ref> DDT resistance can possibly lead to pyrethroid resistance, as both pesticide classes act on the same target site.<ref>http://newyorkvsbedbugs.org/2010/01/21/kdr-pyrethroid-resistance-widespread-in-u-s-bed-bug-populations/</ref>
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Bedbugs have a cuticle on the outside of their body that is almost impenetrable to many insecticides used today, therefore the bugs do not pick up the dried residues of such very well.  Bedbugs developed resistance to DDT in the 1950s, and then to its successors such as organophosphates like diazinon and malathion which were being used to clear up remaining infestations.<ref>http://www.earthfiles.com/news.php?ID=1768&category=Environment</ref> DDT resistance can possibly lead to pyrethroid resistance, as both pesticide classes act on the same target site.<ref>http://newyorkvsbedbugs.org/2010/01/21/kdr-pyrethroid-resistance-widespread-in-u-s-bed-bug-populations/</ref> Entomologists at the University of Kentucky reported that some bed bug populations across the United States are resistant to pyrethroid insecticides, with some showing an 1,000-fold resistance to deltamethrin and lambda-cyhalothrin, compared to a susceptible laboratory strain. Researchers further found that seven of the eight field populations submitted by pest-management firms across the country were well over 100-fold resistant to deltamethrin.<ref>http://web.extension.illinois.edu/ipr/i4145_829.html#5</ref>
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Before developing resistance, use of DDT dust, followed by malathion, diazinon, etc.  (in addition to normal measures such as laundering), was effective in largely eradicating bedbugs in the recent past, as a single thorough application of these older insecticides typically worked as bugs succumbed after crawling or resting contact with previously treated surfaces. As most of today's sprays lack similar residual potency (and with many also being repellent), desiccant (drying) dust formulations may play an increasing role in eliminating and preventing bedbugs in harborage areas.<ref>[http://www.mypmp.net/bed-bugs/bed-bugs-are-dusts-bed-bug-bullet ''Bed Bugs: Are Dusts the Bed Bug Bullet?''] Pest management professional, May, 2009</ref>  
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Before developing resistance, use of DDT dust, followed by malathion, diazinon, etc.  (in addition to normal measures such as cleaning and laundering), was effective in largely eradicating bedbugs in the recent past, as a single thorough application of these older insecticides typically worked as bugs succumbed after crawling or resting contact with previously treated surfaces. As most of today's sprays lack similar residual potency (and with many also being repellent), desiccant (drying) dust formulations may play an increasing role in eliminating and preventing bedbugs in harborage areas.<ref>[http://www.mypmp.net/bed-bugs/bed-bugs-are-dusts-bed-bug-bullet ''Bed Bugs: Are Dusts the Bed Bug Bullet?''] Pest management professional, May, 2009</ref>  
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Repeat treatments with any insecticide are advised and are almost always necessary. Self-treatment is discouraged, and can make eradication much more difficult than when done by professional exterminators, trained in bedbug elimination. Spot treatment of bedbugs with chemical formulations can make matters worse by allowing them to disperse and or develop resistance to the insecticide used.  Inhalation of all  insecticides is to be avoided. Fogging is not advised, as besides the health risk to humans, they are considered to be less effective, and most contain pyrethroids, which has an associated excitatory flushing effect and by spraying into a space rather than harbourage, bugs are likely to disperse and can spread an infestation.<ref>[http://bedbugger.com/2007/05/30/bombs-dont-work-on-bed-bugs-citation-anyone/ Bombs and foggers don’t work on bed bugs and can make them worse]</ref>
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Repeat treatments with any insecticide are advised and are almost always necessary. Self-treatment is discouraged, and can make eradication much more difficult than when done by professional exterminators, trained in bedbug elimination. Spot treatment of bedbugs with chemical formulations can make matters worse by allowing them to disperse and or develop resistance to the insecticide used.  Inhalation of all  insecticides is to be avoided. Fogging is less advised, as besides the health risk to humans, they are considered to be less effective, and most contain pyrethroids, which has an associated excitatory flushing effect and by spraying into a space rather than harbourage, bugs are likely to disperse and can spread an infestation.<ref>[http://bedbugger.com/2007/05/30/bombs-dont-work-on-bed-bugs-citation-anyone/ Bombs and foggers don’t work on bed bugs and can make them worse]</ref>
    
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