Changes

::The second step in transcription initiation involves the unwinding of the DNA between the -10 region and the start site of transcription.  This is referred to as the open complex.

::The second step in transcription initiation involves the unwinding of the DNA between the -10 region and the start site of transcription.  This is referred to as the open complex.

[[Image:Image010.gif|left|thumb|Termination of Prokaryotic Transcription]]

[[Image:Image010.gif|left|thumb|Termination of Prokaryotic Transcription]]

::'''RNA Synthesis'''

::'''RNA Synthesis'''

::Transcription continues until a termination signal is reached.  The current model is that the RNA dissociates from the DNA – RNA hybrid to form a stem-loop structure.  The remaining AU base pairs are not strong enough to keep RNA hybridized with the DNA.  Dissociation of the RNA destabilizes RNA polymerases and transcription terminates.

::Transcription continues until a termination signal is reached.  The current model is that the RNA dissociates from the DNA – RNA hybrid to form a stem-loop structure.  The remaining AU base pairs are not strong enough to keep RNA hybridized with the DNA.  Dissociation of the RNA destabilizes RNA polymerases and transcription terminates.

===Eukaryotic Transcription===

===Eukaryotic Transcription===