| | *[[Malaria]]<ref>[https://www.gavi.org/vaccineswork/worlds-first-ever-malaria-vaccine-approved-we-cannot-let-it-be-last?gclid=EAIaIQobChMIucnpyLfX9QIVAp2zCh2yMQGTEAAYAiAAEgItWvD_BwE Gavi, the Vaccine Alliance]</ref> | | *[[Malaria]]<ref>[https://www.gavi.org/vaccineswork/worlds-first-ever-malaria-vaccine-approved-we-cannot-let-it-be-last?gclid=EAIaIQobChMIucnpyLfX9QIVAp2zCh2yMQGTEAAYAiAAEgItWvD_BwE Gavi, the Vaccine Alliance]</ref> |
| | + | Fear of polio in the U.S. was second only to fear of nuclear war, in the post-war years, until [[Jonas Salk]] developed an effective vaccine. [https://www.history.com/news/8-things-you-may-not-know-about-jonas-salk-and-the-polio-vaccine] Most cases (about 95%) of polio are asymptomatic, or cause minor respiratory or gastrointestinal symptoms. About 1 of every 1000 cases leads to paralytic polio. |
| | + | *Oral Polio Vaccine (OPV). This vaccine makes use of a live-attenuated form of the [[virus]]. It is administered orally, infects the host, and is spread in the same way as polio. It does not cause paralytic polio. One advantage of this vaccine is that it can "passively" vaccinate those who do not get vaccinated normally. Unfortunately, immunocompromised people can become quite ill from exposure, so this vaccine is largely being replaced in the US. |
| | [[Edward Jenner]] ( 1749 – 1823) discovered that milkmaids developed an immunity to [[smallpox]], because they had earlier contacted cowpox. Cowpox is an uncommon, mild disease of animals, first observed in cows, closely related to the virus which causes smallpox. This led to the invention of a smallpox vaccine, which Jenner first tested in May 14, 1796, by inoculating eight-year-old James Phipps, the son of his gardener.<ref>Stefan Riedel, MD (January 2005). "Edward Jenner and the history of smallpox and vaccination". Proceedings (Baylor University. Medical Center). Baylor University Medical Center. 18 (1): 21–25.</ref> | | [[Edward Jenner]] ( 1749 – 1823) discovered that milkmaids developed an immunity to [[smallpox]], because they had earlier contacted cowpox. Cowpox is an uncommon, mild disease of animals, first observed in cows, closely related to the virus which causes smallpox. This led to the invention of a smallpox vaccine, which Jenner first tested in May 14, 1796, by inoculating eight-year-old James Phipps, the son of his gardener.<ref>Stefan Riedel, MD (January 2005). "Edward Jenner and the history of smallpox and vaccination". Proceedings (Baylor University. Medical Center). Baylor University Medical Center. 18 (1): 21–25.</ref> |