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'''RNase P''' is a ribozyme with ribonuclease (RNA cutting) activity found in all known forms of cellular life. It is responsible for processing precursor-tRNAs as well as precursors to some other functional RNAs within the cell.<ref>http://rna.cshl.edu/content/free/chapters/14_rna_world_2nd.pdf</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pubmed/9759486</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC148169/pdf/270314.pdf</ref>

Ribozymes are currently a centerpiece in the ongoing debate on the origin of life. The ability of some RNA polymerizing ribozymes to synthesize functional products without the need for a [[DNA]] template<ref>httphttps://www.ncbi.nlm.nih.gov/pubmed/11358999</ref> (they use an RNA template instead) makes RNA an attractive candidate for hypothetical primitive [[biochemistry]]. There is a growing body of chemical, [[molecular biology|molecular biological]], and [[geology|geological]] evidence which supports this hypothesis.<ref>http://www.nature.com/nature/journal/v459/n7244/full/nature08013.html</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673073/pdf/743.pdf</ref><ref>http://bonhamchemistry.com/wp-content/uploads/2012/01/RNA_World.pdf</ref><ref>http://www.springerlink.com/content/k84710318l244777/</ref><ref>http://dasher.wustl.edu/bio5357/reading/nature-418-214-02.pdf</ref><ref>http://auditore.cab.inta-csic.es/manrubia/files/2012/09/OLEB40-429.pdf</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293468/pdf/nihms78555.pdf</ref> Additionally, the recent development of a self-replicating ribozyme derived from a viral ribozyme,<ref>http://www.pnas.org/content/99/20/12733.full.pdf+html</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pubmed/22551009</ref> demonstrates that self-replicating RNAs ''can'' exist. However, the evidence remains largely circumstantial as nothing conclusive has been found thus far and, even among biochemists, the hypothesis does have its detractors.<ref>http://www.biology-direct.com/content/pdf/1745-6150-7-23.pdf</ref>