| − | [[Chemotherapy]] is the use of drugs that kill [[tumor]] cells. Conventionally, the drugs that are used are those that target cells which are rapidly undergoing [[mitosis]]; this approach is effective but is limited by side effects, and the dose that is effective in killing cancer cells also has an adverse effect on other tissues such as those that are responsible for the regeneration of blood cells. Research is under way to find improved medicines for this purpose; one approach is to study specific molecular markers that may be used to identify cancer cells, and to develop drugs that preferentially kill cells that exhibit those markers. | + | [[Chemotherapy]] is the use of drugs that kill [[tumor]] cells. Conventionally, the drugs that are used are those that target cells which are rapidly undergoing [[mitosis]]; this approach is effective but is limited by side effects, which occur because these drugs have an adverse effect on normal tissues that contain rapidly-dividing cells. Research is under way to find drugs with a wider [[therapeutic margin]]. One approach is to study specific molecular markers that may be used to identify cancer cells, and to develop drugs that preferentially kill cells that exhibit those markers. |