Follicles are located in the outer cortex of a female's ovary. Initially 6-7 million primordial follicles are developed during oogenesis, however one 2 million are present at birth, 500,000 at puberty and around 1000 by menopause. One of the causes of menopause is the low number of follicles being able to produce estrogen to drive the menstrual cycle. | Follicles are located in the outer cortex of a female's ovary. Initially 6-7 million primordial follicles are developed during oogenesis, however one 2 million are present at birth, 500,000 at puberty and around 1000 by menopause. One of the causes of menopause is the low number of follicles being able to produce estrogen to drive the menstrual cycle. |