Chance
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Chance is an apparently random occurrence of an event. An entire branch of mathematics known as probability and statistics is devoted to studying and analyzing chance.
In many Christian faiths true chance does not exist, as God has a preordained purpose for everything. Chance therefore reflects man's limitations on understanding rather than an underlying causality or lack of purpose.
Albert Einstein famously criticized the central role of chance in the theory of quantum mechanics by declaring, "God does not play dice."