While campaigning in 1944, Luce's 19 year-old daughter Ann Clare was killed in an automobile accident.<ref name=nytimes/> The tragedy ended some of her political hopes, and she declined to seek re-election to a third House term in the [[1946 Midterm Elections|1946 midterms]].<ref name=history.house.gov/>
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While campaigning in 1944, Luce's 19 year-old daughter Ann Clare was killed in an automobile accident.<ref name=nytimes/> The tragedy ended some of her political hopes, and she declined to seek re-election to a third House term in the [[1946 Midterm Elections|1946 midterms]].<ref name=history.house.gov/> When talking to Catholic bishop Fulton J. Sheen, she asked: "Listen, if God is good, why did He take my daughter?"<ref name=nytimes/>
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After conferring with Sheen for some time, Luce converted to Roman Catholicism in 1946. A friend said of her transition:<ref name=nytimes/>
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{{cquote|Twenty years ago she was like a diamond – beautiful, brilliant and cold. Now she is beautiful, brilliant and compassionate. She has become a kind and remarkably unselfish woman.}}