But this ended their attempt after 22,000 of them died, mostly due to yellow fever. Some 5,609 Americans died in the subsequent successful attempt to build the canal, the lower number reflecting medical advances of the time. | But this ended their attempt after 22,000 of them died, mostly due to yellow fever. Some 5,609 Americans died in the subsequent successful attempt to build the canal, the lower number reflecting medical advances of the time. |