Changes

== Richard Lenski incorrectly included generations of the E. coli already known to contain Cit+ variants in his experiments.[3] Once these generations are removed from the analysis, the data disprove Len ==

== Richard Lenski incorrectly included generations of the E. coli already known to contain Cit+ variants in his experiments.[3] Once these generations are removed from the analysis, the data disprove Len ==

The author of the above statement must not have read the paper or the supplement carefully. Lenski took clones from those cultures that '''weren't Cit+'''. Careful reading of the paper or the supplement reveals that Cit+ mutants appeared at 750 generations or later into the replay experiment. The authors write: "New Cit+ variants emerged between 750 and 3,700  generations..."

The author of the above statement must not have read the paper or the supplement carefully. Lenski took clones from those cultures that '''weren't Cit+'''. Careful reading of the paper or the supplement reveals that Cit+ mutants appeared at 750 generations or later into the replay experiment. The authors write: "New Cit+ variants emerged between 750 and 3,700  generations..."--[[User:Argon|Argon]] 15:03, 13 July 2008 (EDT)

== 1. Lenski's "historical contingency" hypothesis, as specifically depicted in Figure 3, is contradicted by the data presented... ==

== 1. Lenski's "historical contingency" hypothesis, as specifically depicted in Figure 3, is contradicted by the data presented... ==

Again, more issues with comprehension: The authors did not know when the potentiating mutation first arose but they knew it was before generation 31,500. Figure 2 is merely figurative, being an illustration, and not quantitative. Their analyses suggested that the potentiating mutation did arise at about the 20,000 generation point or later. Their conclusion is that Cit+ mutation rate is low even in a potentiated background but apparently distinguishable from a low-incidence single, unpotentiated event.

Again, more issues with comprehension: The authors did not know when the potentiating mutation first arose but they knew it was before generation 31,500. Figure 2 is merely figurative, being an illustration, and not quantitative. Their analyses suggested that the potentiating mutation did arise at about the 20,000 generation point or later. Their conclusion is that Cit+ mutation rate is low even in a potentiated background but apparently distinguishable from a low-incidence single, unpotentiated event.