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::Blount et al. discussed the unexpectedly low Cit+ conversion rate for the third replay set in the supplementary document. They have some speculations but don't know why it occurred. They are dealing with low probability events. I don't agree that the 'proper' interpretation is contamination. First, they isolated and tested each Cit+ isolate for the markers and sequences we've discussed on earlier Conservapedia pages. Second, the distribution of Cit+ isolates does not appear to be random: They correlate strongly with the later generations. If undetected contamination was random, it's unlikely the Monte Carlo resampling tests would reject the null hypothesis of the 'rare-mutation' hypothesis over the 'potentiated' hypothesis. As Brossa correctly notes, contamination would have affected all generations. Blount et al. write in the paper's supplement: "To facilitate handling and minimize possible confounding variables, we divided this third experiment into 20 blocks of 14 clones each. All of the clones within a block came from different generations, and the single ancestral clone was included in all 20 blocks."--[[User:Argon|Argon]] 20:01, 15 July 2008 (EDT)
 
::Blount et al. discussed the unexpectedly low Cit+ conversion rate for the third replay set in the supplementary document. They have some speculations but don't know why it occurred. They are dealing with low probability events. I don't agree that the 'proper' interpretation is contamination. First, they isolated and tested each Cit+ isolate for the markers and sequences we've discussed on earlier Conservapedia pages. Second, the distribution of Cit+ isolates does not appear to be random: They correlate strongly with the later generations. If undetected contamination was random, it's unlikely the Monte Carlo resampling tests would reject the null hypothesis of the 'rare-mutation' hypothesis over the 'potentiated' hypothesis. As Brossa correctly notes, contamination would have affected all generations. Blount et al. write in the paper's supplement: "To facilitate handling and minimize possible confounding variables, we divided this third experiment into 20 blocks of 14 clones each. All of the clones within a block came from different generations, and the single ancestral clone was included in all 20 blocks."--[[User:Argon|Argon]] 20:01, 15 July 2008 (EDT)
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::: Good and detailed analyis and conclusion, Argon. I had no time to read everything in that detail, but i think you present exactly the arguments (contant background would favour rare mutation hypothesis) would be exactly the one i had in mind, so let's see how Mr. Schlafly will bend his own Monte-Carlo simulations to showing several 1000 times no mutation into accordance with any reasonable background explaining a significant number of counts in *some* samples --[[User:Stitch75|Stitch75]] 20:20, 15 July 2008 (EDT)
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