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Talk:PNAS Response to Letter (view source)
Revision as of 13:55, September 17, 2008
, 13:55, September 17, 2008→Improper
:: Biological studies routinely require at least some application of statistical theory, especially when studying populations of organisms or molecules which molecular (and evolutionary) biology usually involves. Biostatistics (the statistical theories commonly used in biomedicine) is often a required course for PhD students for this reason. Established researchers in the life sciences do not need to have a degree in statistics to indicate expertise - Lenski's publication record itself indicates that he has successfully applied statistical theory in his analyses many times. At any rate, if someone can simply claim without proof that he has taken (and understood) statistics courses on the level needed to evaluate Lenski's paper, then he has no basis on which to accuse others of lacking expertise.
:: Biological studies routinely require at least some application of statistical theory, especially when studying populations of organisms or molecules which molecular (and evolutionary) biology usually involves. Biostatistics (the statistical theories commonly used in biomedicine) is often a required course for PhD students for this reason. Established researchers in the life sciences do not need to have a degree in statistics to indicate expertise - Lenski's publication record itself indicates that he has successfully applied statistical theory in his analyses many times. At any rate, if someone can simply claim without proof that he has taken (and understood) statistics courses on the level needed to evaluate Lenski's paper, then he has no basis on which to accuse others of lacking expertise.
::: Malarkey. I've taken and excelled in upperclass statistics courses, and there were not biology students, college or graduate, in them. If Lenski has expertise in statistics then let's see it. His own "biographical sketch" doesn't even disclose what his undergraduate major was at Oberlin or what his PhD concentration at the University of North Carolina were in.[http://myxo.css.msu.edu/BioSketch.html]--[[User:Aschlafly|Aschlafly]] 19:26, 16 September 2008 (EDT)
::: Malarkey. I've taken and excelled in upperclass statistics courses, and there were not biology students, college or graduate, in them. If Lenski has expertise in statistics then let's see it. His own "biographical sketch" doesn't even disclose what his undergraduate major was at Oberlin or what his PhD concentration at the University of North Carolina were
in.[http://myxo.css.msu.edu/BioSketch.html]--[[User:Aschlafly|Aschlafly]] 19:26, 16 September 2008 (EDT)
::::Andy, the bottom line is the PNAS publishes letters online criticizing their publication all the time. Every single issue. It's the whole function of "Letters to the PNAS". It's the only reason the letters section of the PNAS exists. They would have published your letter if it had shown the requisite understanding of the issues at hand. How do we know this? Because they do it all the time. Why didn't they publish yours? Because your understanding of how to statistically analyze experiments involving bacteria populations isn't up to snuff. How could it be? A man who was truly interested in learning would show humility, accept criticism, and dive into the relevant literature about Monte Carlo, z-transformations, etc. A man who was only interested in protecting his ego would carry on the lie that Lenski and the PNAS don't know what they are talking about. [[User:KimEide|KimEide]] 09:27, 17 September 2008 (EDT)
::::Andy, the bottom line is the PNAS publishes letters online criticizing their publication all the time. Every single issue. It's the whole function of "Letters to the PNAS". It's the only reason the letters section of the PNAS exists. They would have published your letter if it had shown the requisite understanding of the issues at hand. How do we know this? Because they do it all the time. Why didn't they publish yours? Because your understanding of how to statistically analyze experiments involving bacteria populations isn't up to snuff. How could it be? A man who was truly interested in learning would show humility, accept criticism, and dive into the relevant literature about Monte Carlo, z-transformations, etc. A man who was only interested in protecting his ego would carry on the lie that Lenski and the PNAS don't know what they are talking about. [[User:KimEide|KimEide]] 09:27, 17 September 2008 (EDT)
::::Andy, no offense, but when I referred to my own statistics knowledge and suggested that I saw no problem with the two examples picked out above, you left me warning that included tell me not to appeal to my own "expertise". I don't see why this is any different?
::::I still, having read your previous comments on the original letter, don't feel that you've explained either a) why the use of Monte Carlo was wrong, b) why the use of Z-transformation was wrong, nor c) critically, what alternative analysis you would have used, and what p-values you would have obtained with it. That last point is what I feel you really need to address if you want PNAS to really take notice.
::::Additionally, graduate level statistics is really quite basic by scientific standards. The gap between a Ph.D. and degree level knowledge is like the gap between a degree and junior high school. Biology as a field is hugely intertwined with complex statistics, and many biologists will have gained an understanding well beyond graduate level.
::::I'm not "anti" this letter, I'm not a liberal agitator, I've made decent contributions in my time here, but I really feel that this letter needs somebody to just take a step back, and consider that maybe the first attempt can be improved. As I mentioned previously, I think some good, proactive steps would be to concentrate more on the missing data claim, and to bring on board somebody with an expert knowledge of statistics or biology to help refine the claims, and double check whether you're right on some of these points or not. [[User:MikeR|MikeR]] 09:55, 17 September 2008 (EDT)
==Clarification on peer review and anonymity==
==Clarification on peer review and anonymity==