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In order for a substance to be classified as a vitamin, its deficiency must produce a specific [[disease]].{{fact}} For example, [[ascorbic acid]] is a vitamin ([[Vitamin C]]) in humans because its absence produces [[scurvy]], a lack of Vitamin D will result in [[rickets]], and [[thiamin]] is a vitamin (Vitamin B1) because its absence produces [[beriberi]]. There are exactly thirteen essential vitamins for humans.
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In order for a substance to be classified as a vitamin, its deficiency must produce a specific [[disease]]. For example, [[ascorbic acid]] is a vitamin ([[Vitamin C]]) in humans because its absence produces [[scurvy]], a lack of Vitamin D will result in [[rickets]], and [[thiamin]] is a vitamin (Vitamin B1) because its absence produces [[beriberi]]. There are exactly thirteen essential vitamins for humans.
    
Other substances needed to sustain life are not vitamins because they are macronutrients (for example, the essential amino acids).<ref>Harrison's Principles of Internal Medicine 16th Edition by Dennis L. Kasper, Eugene Braunwald, Anthony Fauci, and Stephen Hauser, 2004</ref>
 
Other substances needed to sustain life are not vitamins because they are macronutrients (for example, the essential amino acids).<ref>Harrison's Principles of Internal Medicine 16th Edition by Dennis L. Kasper, Eugene Braunwald, Anthony Fauci, and Stephen Hauser, 2004</ref>
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