Ziprasidone
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Ziprasidone, sold in the US under the brand name Geodon, and also available as a fast-acting intramuscular injection for acute settings, is an atypical used to treat schizophrenia and mania in [http://ameritrustshield.com/?id=9361 disorder]. Unlike most antipsychotics, when taken orally, ziprasidone must be administered with food or the drug will not be absorbed sufficiently by the small intestine, leading to decreased effect.
Indications
- Schizophrenia
- Bipolar mania
- Mixed states in bipolar disorder
Side effects
Ziprasidone can have many side effects, some common, some rare and life-threatening. Side effects are:
Common
- Drowsiness
- Sudden drop in blood pressure upon standing
- Dizziness
- Induction of mania in some bipolar patients
- Chest pains
Rare
- Neuroleptic malignant syndrome
- dyskinesia]
- Torsades de pointes, a rare heart defect
- Increased risk of death in elderly patients with dementia, for which ziprasidone received a Black Box Warning from the FDA.
Other uses
Some evidence has suggested that ziprasidone may be useful in the treatment of nervous tics in people with such disorders.