It is named for the St. Louis and San Francisco Railway (commonly called the "Frisco", now part of BNSF Railway) which runs through the town; the city's logo is the railway's original logo and is used by permission.
The city refers to itself as "Sports City, USA", and all five of the DFW Metroplex's sports franchises have operations in the city:
- Dallas Cowboys (football) - headquarters and practice facility
- Texas Rangers (baseball) - AA affiliate (Frisco RoughRiders)
- Dallas Mavericks (basketball) - G-League affiliate (Texas Legends)
- Dallas Stars (hockey) - headquarters and practice facility
- FC Dallas (soccer) - home field, headquarters and practice facility
The Professional Golfers Association of America announced plans in late 2018 to move its headquarters to Frisco from West Palm Beach, Florida, expected to be completed in 2020.
The NCAA Football Championship Series national championship game is played in Frisco in early January of each year.