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Lyon was a member of the Petroleum Club, the Houston Club, the University Club, and the River Oaks Country Club. He founded the James E. Lyon Medical Research Foundation, which underwrites cancer research. He was also a board member of St. Joseph's Hospital Foundation, a member of the Rice University Associates, and a member of the president's council of Houston Baptist University.<ref name=obit/>

Lyon was a member of the Petroleum Club, the Houston Club, the University Club, and the River Oaks Country Club. He founded the James E. Lyon Medical Research Foundation, which underwrites cancer research. He was also a board member of St. Joseph's Hospital Foundation, a member of the Rice University Associates, and a member of the president's council of Houston Baptist University.<ref name=obit/>

   

   

Lyon died at his home in Houston at the age of sixty-five. He was survived by his wife, Desiree; his mother, Virginia Asbell Lyon Hedrick (1904-2000), a native of [[Pierre, South Dakota|Pierre]], [[South Dakota]], who was formerly a lecturer for the [[Dale Carnegie]] company;<ref name=valh>{{cite web|url=http://www.chron.com/CDA/archives/archive.mpl/obits_3379020/virginia-asbell-lyon-hedrick.html|title-Obituary oif Virginia Asbell Lyon Hedrick|publisher=''Houston Chronicle'', February 7, 2000|accessdate=April 14, 2012}}</ref> daughters, Dana Lyon, Melissa Lyon Simon and her husband, Terry Simon, and Jennifer Stewart Lyon, all of Houston; stepdaughter Lelia Dodson; sister and brother-in-law, Connie Bruce and her husband, Homer Lindsay Bruce, since deceased; brother and sister-in-law L. Willard and Chris Hedrick of Oceanside, [[California]],<ref name=valh/> and then six grandchildren.<ref name=obit/>  

Lyon died at his home in Houston at the age of sixty-five. He was survived by his wife, Desiree; his mother, Virginia Asbell Lyon Hedrick (1904-2000), a native of [[Pierre]], [[South Dakota]], who was formerly a lecturer for the [[Dale Carnegie]] company;<ref name=valh>{{cite web|url=http://www.chron.com/CDA/archives/archive.mpl/obits_3379020/virginia-asbell-lyon-hedrick.html|title=Obituary oif Virginia Asbell Lyon Hedrick|publisher=''Houston Chronicle'', February 7, 2000|accessdate=April 14, 2012}}</ref> daughters, Dana Lyon, Melissa Lyon Simon and her husband, Terry Simon, and Jennifer Stewart Lyon, all of Houston; stepdaughter Lelia Dodson; sister and brother-in-law, Connie Bruce and her husband, Homer Lindsay Bruce, since deceased; brother and sister-in-law L. Willard and Chris Hedrick of Oceanside, [[California]],<ref name=valh/> and then six grandchildren.<ref name=obit/>  

Services were held at the Second [[Baptist]] Church sanctuary in Houston. Lyon's obituary does not mention his grave site, but his mother was interred some seven years later at Forest Park Westheimer Cemetery in Houston.<ref name=valh/>

Services were held at the Second [[Baptist]] Church sanctuary in Houston. Lyon's obituary does not mention his grave site, but his mother was interred some seven years later at Forest Park Westheimer Cemetery in Houston.<ref name=valh/>