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'''Archaea''' is one of the three [[Domain (biology)|domains]] of life (the other two being [[prokaryote|prokaryotes]] and [[eukaryote|eukarya]]). It comprises single-celled organisms, similar in size and shape to prokaryotes, that, like prokaryotes, lack internally compartmentalized [[organelles]]. It was established as a separate domain from prokaryotes after biochemical and genetic studies revealed that archaeans formed a genetically distinct group, with distinctive biochemistry (notably in the lipid composition of their cell membranes) and metabolic pathways.