The re-absorptive machinery in the kidneys is so efficient that only 1 liter of urine is produced for every ~100 liters of primary filtrate produced in the glomerulus. This efficiency is important physiologically because it allows the body to conserve water and salts. [[Diabetes insipidus]] is a disease state in which the ability of the kidneys to reabsorb water is somehow compromised, usually due to a deficiency in the hormone [[vasopressin]] (AVP). | The re-absorptive machinery in the kidneys is so efficient that only 1 liter of urine is produced for every ~100 liters of primary filtrate produced in the glomerulus. This efficiency is important physiologically because it allows the body to conserve water and salts. [[Diabetes insipidus]] is a disease state in which the ability of the kidneys to reabsorb water is somehow compromised, usually due to a deficiency in the hormone [[vasopressin]] (AVP). |