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| year= 2008
 
| year= 2008
 
| isbn =  
 
| isbn =  
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| pages = 36-76
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| pages = 36–76
 
| url=
 
| url=
 
| quote= }}</ref> The American philosopher and logician [[Charles Sanders Peirce]] was the first to describe it. As he noted, the problem with abductive reasoning is that there is often more than one cause that can explain the same effect. He suggested that a particular abductive hypothesis can be firmly established if it can be shown that it represents the best or only explanation of the "manifest effects" in question.<ref name="Signature">{{Cite book
 
| quote= }}</ref> The American philosopher and logician [[Charles Sanders Peirce]] was the first to describe it. As he noted, the problem with abductive reasoning is that there is often more than one cause that can explain the same effect. He suggested that a particular abductive hypothesis can be firmly established if it can be shown that it represents the best or only explanation of the "manifest effects" in question.<ref name="Signature">{{Cite book
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| year= 2008
 
| year= 2008
 
| isbn = 978-0-06-147279-2
 
| isbn = 978-0-06-147279-2
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| pages = 153-156
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| pages = 153–156
 
| url=http://books.google.no/books?id=RUGKBdKawDUC&dq=signature+in+the+cell&hl=en&sa=X&ei=k4o9T-HHFaSF4gTYqpSSCA&ved=0CDEQ6AEwAQ
 
| url=http://books.google.no/books?id=RUGKBdKawDUC&dq=signature+in+the+cell&hl=en&sa=X&ei=k4o9T-HHFaSF4gTYqpSSCA&ved=0CDEQ6AEwAQ
 
| quote= }}</ref>
 
| quote= }}</ref>
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