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→Explanatory Filter Step 1 – Ruling Necessity In or Out: clean up & uniformity
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So in building models we would postulate that the sugar-phosphate backbone was very regular, and the order of bases of necessity very irregular. If the base sequences were always the same, all DNA molecules would be identical and there would not exist the variability that must distinguish one gene from another. <ref>James Watson, '''The Double Helix: A Personal Account of the Discovery of THE STRUCTURE OF DNA''', (Touchstone 1968) p 52-4.</ref>
So in building models we would postulate that the sugar-phosphate backbone was very regular, and the order of bases of necessity very irregular. If the base sequences were always the same, all DNA molecules would be identical and there would not exist the variability that must distinguish one gene from another.<ref>James Watson, '''The Double Helix: A Personal Account of the Discovery of THE STRUCTURE OF DNA''', (Touchstone 1968) p 52-4.</ref>
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