Changes

'''Leukocidin''' (also spelled '''Leucocidin''') is a bacterial cytoxic protein consisting of two components which act in accord to induce cytotoxic changes in [[leukocytes]], as well as other cells, such as connective tissue cells and the cells of the sympathetic nervous system.<ref name=Definition>{{cite book|author=Maurice Bartlett Hallett|title=The Neutrophil: Cellular Biochemistry and Physiology|url=http://books.google.com/books?id=eD9WxY7lzrEC&pg=PA180&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDsQ6AEwAQ#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=Leukocodicin is a cytoxic protein produced by bacteria, e.g., ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''. It consists of two components which act syngergistically to induce cytotoxic changes in neutrophils, macrophages, and lymphocytes, but not erythrocytes or platelets. The mode of leukocidin is unknown, but it has been reported that it leads to an accumulation of Ca²⁺ which is accompanied by secretion.|publisher=CRC Press|date=31 January 1989|accessdate=10 June 2012|page=180|isbn=0849348080}}</ref><ref name=Cells>{{cite book|title=The Journal of Infectious Diseases: Volume 27|url=http://books.google.com/books?id=7jjQAAAAMAAJ&pg=PA87&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDMQ6AEwAA#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=According to Deny and Van de Velde,' staphylococcus leukocidin is a metabolic product that acts not only on leukocytes, but on other cells, such as connective tissue cells and the cells of the sympathetic nervous system.|publisher=University of Chicago Press|year=1920|accessdate=10 June 2012|page=87|isbn=0849348080}}</ref> Leukocidin is produced specifically by ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''.<ref name=Definition>{{cite book|author=Maurice Bartlett Hallett|title=The Neutrophil: Cellular Biochemistry and Physiology|url=http://books.google.com/books?id=eD9WxY7lzrEC&pg=PA180&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDsQ6AEwAQ#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=Leukocodicin is a cytoxic protein produced by bacteria, e.g., ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''. It consists of two components which act syngergistically to induce cytotoxic changes in neutrophils, macrophages, and lymphocytes, but not erythrocytes or platelets. The mode of leukocidin is unknown, but it has been reported that it leads to an accumulation of Ca²⁺ which is accompanied by secretion.|publisher=CRC Press|date=31 January 1989|accessdate=10 June 2012|page=180|isbn=0849348080}}</ref> The cytotoxin is released by the bacteria through an accumulation of intracellular [[calcium]].<ref name=Definition>{{cite book|author=Maurice Bartlett Hallett|title=The Neutrophil: Cellular Biochemistry and Physiology|url=http://books.google.com/books?id=eD9WxY7lzrEC&pg=PA180&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDsQ6AEwAQ#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=Leukocodicin is a cytoxic protein produced by bacteria, e.g., ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''. It consists of two components which act syngergistically to induce cytotoxic changes in neutrophils, macrophages, and lymphocytes, but not erythrocytes or platelets. The mode of leukocidin is unknown, but it has been reported that it leads to an accumulation of Ca²⁺ which is accompanied by secretion.|publisher=CRC Press|date=31 January 1989|accessdate=10 June 2012|page=180|isbn=0849348080}}</ref>

'''Leukocidin''' (also spelled '''Leucocidin''') is a bacterial cytoxic protein consisting of two components which act in accord to induce cytotoxic changes in [[leukocytes]], as well as other cells, such as connective tissue cells and the cells of the sympathetic nervous system.<ref name=Definition>{{cite book|author=Maurice Bartlett Hallett|title=The Neutrophil: Cellular Biochemistry and Physiology|url=http://books.google.com/books?id=eD9WxY7lzrEC&pg=PA180&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDsQ6AEwAQ#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=Leukocodicin is a cytoxic protein produced by bacteria, e.g., ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''. It consists of two components which act syngergistically to induce cytotoxic changes in neutrophils, macrophages, and lymphocytes, but not erythrocytes or platelets. The mode of leukocidin is unknown, but it has been reported that it leads to an accumulation of Ca²⁺ which is accompanied by secretion.|publisher=CRC Press|date=31 January 1989|accessdate=10 June 2012|page=180|isbn=0849348080}}</ref><ref name=Cells>{{cite book|title=The Journal of Infectious Diseases: Volume 27|url=http://books.google.com/books?id=7jjQAAAAMAAJ&pg=PA87&dq=%22leukocidin+is+a%22&hl=en&sa=X&ei=XUPVT_uvEKjy2QWM69yYDw&ved=0CDMQ6AEwAA#v=onepage&q=%22leukocidin%20is%20a%22&f=false|quote=According to Deny and Van de Velde,' staphylococcus leukocidin is a metabolic product that acts not only on leukocytes, but on other cells, such as connective tissue cells and the cells of the sympathetic nervous system.|publisher=University of Chicago Press|year=1920|accessdate=10 June 2012|page=87|isbn=0849348080}}</ref> Leukocidin is produced specifically by ''Pseudomonos aeruginosa'' and ''Staphylococcus aureus''.<ref name="Definition"/> The cytotoxin is released by the bacteria through an accumulation of intracellular [[calcium]].<ref name="Definition"/>

==References==

==References==