Administration of heroin is typically conducted intravenously (sometimes mixed with [[cocaine]], a combination known as a 'speedball'), insufflated, or smoked (referred to colloquially as 'chasing the dragon'). Large doses of heroin can be fatal. | Administration of heroin is typically conducted intravenously (sometimes mixed with [[cocaine]], a combination known as a 'speedball'), insufflated, or smoked (referred to colloquially as 'chasing the dragon'). Large doses of heroin can be fatal. |