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2,021 bytes added ,  05:49, February 17, 2017
change active to psychoactive; note endocannabinoid basis; prescribed by a physician is sufficient; add research cannabinoid ligands as anticancer agents; add anticonvulsant; Marinol is synthetic, not plant sourced; add reason MDs won't prescribe MM; a...
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[[Image:Marijuana.jpg|thumb|250px|right|Indoor Marijuana Grow (DEA photo)]]
 
[[Image:Marijuana.jpg|thumb|250px|right|Indoor Marijuana Grow (DEA photo)]]
'''Marijuana''' (colloquially known as '''"weed"''' or '''"pot"''') is the name given to the flowering buds of the cannabis sativa plant prepared for human consumption. The main active ingredient in marijuana is [[Tetrahydrocannabinol|THC]], or delta-9-tetrahydrocannabinol, an [[organic chemistry|organic chemical]] compound. Marijuana is harmful and generally illegal to possess, cultivate and sell in most countries, although it is legal in a few liberal jurisdictions if prescribed as "medication" by a physician.<ref>The sale of marijuana is illegal virtually everywhere in the world, and results in long prison sentences in many places. In Portugal, Argentina, California and South Australia, the use (rather than the sale) of small quantities of marijuana is allowed. In only one country in the world, the Netherlands, the sale of marijuana in small quantities is reportedly allowed by law enforcement.</ref>  The crime rate in Denver has skyrocketed by 44% since marijuana was legalized in that state.
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'''Marijuana''' (colloquially known as '''"weed"''' or '''"pot"''') is the name given to the flowering buds of the cannabis sativa plant prepared for human consumption. The main psychoactive ingredient in marijuana is [[tetrahydrocannabinol|THC]], or delta-9-tetrahydrocannabinol, an [[organic chemistry|organic chemical]] compound which imitates natural cannabinoids produced in the human body. Because marijuana is considered harmful it is generally illegal to possess, cultivate and sell in most countries, although it is legal in a some liberal jurisdictions when prescribed as by a physician.<ref>The sale of marijuana is illegal virtually everywhere in the world, and results in long prison sentences in many places. In Portugal, Argentina, California and South Australia, the use (rather than the sale) of small quantities of marijuana is allowed. In only one country in the world, the Netherlands, the sale of marijuana in small quantities is reportedly allowed by law enforcement.</ref>  The crime rate in Denver has skyrocketed by 44% since marijuana was legalized in that state.
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In the past two decades, the number of brain tumors has increased by up to 40% in the U.S. and Europe, particularly among men between ages of 20 and 40<ref>http://www.healthandenvironment.org/brain_cancer/peer_reviewed</ref> - the same demographic that is most likely to have smoked pot.
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In the past two decades, the number of brain tumors has increased by up to 40% in the U.S. and Europe, particularly among men between ages of 20 and 40<ref>http://www.healthandenvironment.org/brain_cancer/peer_reviewed</ref> the same demographic that is most likely to have smoked pot. However, conclusions based on a review of published biomedical research find that cannabinoid compounds unique to cannabis actually exhibit promising anticancer properties, reducing both tumor size and cancer pain.<ref>{{Cite journal|last=Nikan|first=Marjan|last2=Nabavi|first2=Seyed Mohammad|last3=Manayi|first3=Azadeh|date=2016-02-01|title=Ligands for cannabinoid receptors, promising anticancer agents|url=https://www.ncbi.nlm.nih.gov/pubmed/26764235|journal=Life Sciences|volume=146|pages=124–130|doi=10.1016/j.lfs.2015.12.053|issn=1879-0631|pmid=26764235}}</ref>
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The [[liberal media]] typically downplay or completely ignore the role of marijuana in [[Young mass murderers|mass killings]], horrific accidents, and other types of harm to innocent people victimized by users of the drug.  For example, authorities conceal from the public how much marijuana was in the system of "College Weed Dealer" [[Young Mass Murderers|Dzhokhar Tsarnaev]] when he went on his killing rampage.<ref>http://www.theatlanticwire.com/national/2013/04/dzhokhar-tsarnaev-dealing-drugs/64529/</ref>  ''Rolling Stone'' magazine, which has often featured drug abusers, displayed Dzhokhar Tsarnaev on its cover in July 2013.
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The [[liberal media]] typically downplay or completely ignore the role of marijuana in [[Young mass murderers|mass killings]], horrific accidents, and other types of harm to innocent people victimized by users of the drug.  For example, authorities conceal from the public how much marijuana was in the system of "College Weed Dealer" [[Young Mass Murderers|Dzhokhar Tsarnaev]] when he went on his killing rampage.<ref>http://www.theatlanticwire.com/national/2013/04/dzhokhar-tsarnaev-dealing-drugs/64529/</ref>  ''Rolling Stone'' magazine, which has often featured drug abusers, displayed Dzhokhar Tsarnaev on its cover in July 2013.  
    
The effects of marijuana can include short-term memory loss, malaise, psychosis in predisposed individuals, violence and violent fits, as well as impairment of physical and mental functioning. Some researchers claim that cannabis has "medicinal" benefits (see [[Medical marijuana]]); but many scientists contest this, and state that there are numerous federally approved medicines for the diseases that "medicinal" marijuana has been used to treat.
 
The effects of marijuana can include short-term memory loss, malaise, psychosis in predisposed individuals, violence and violent fits, as well as impairment of physical and mental functioning. Some researchers claim that cannabis has "medicinal" benefits (see [[Medical marijuana]]); but many scientists contest this, and state that there are numerous federally approved medicines for the diseases that "medicinal" marijuana has been used to treat.
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In addition to the claimed positive effect on cancer treatment symptoms and cancer itself, marijuana is used to try to help patients afflicted with [[amyotrophic lateral sclerosis|ALS]].<ref>[http://ajh.sagepub.com/content/18/4/264.short American Journal of Hospice and Palliative Medicine]</ref>
 
In addition to the claimed positive effect on cancer treatment symptoms and cancer itself, marijuana is used to try to help patients afflicted with [[amyotrophic lateral sclerosis|ALS]].<ref>[http://ajh.sagepub.com/content/18/4/264.short American Journal of Hospice and Palliative Medicine]</ref>
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Marijuana is an [[antispasmodic]] and is used in the treatment of seizures.<ref>[http://www.nap.edu/openbook.php?record_id=9586&page=106 National Academies Press: Marijuana and muscle spasticity]</ref> Marijuana is also used in the treatment of migraines, arthritis,<ref>[http://onlinelibrary.wiley.com/doi/10.1002/art.1780090304/abstract Online Library: Treatment of adjuvant arthritis in rats with anti-inflammatory drugs]</ref> depression,<ref name="interestingfacts.org">[http://www.interestingfacts.org/fact/facts-about-marijuana Interesting Facts: Facts about marijuana]</ref> and glaucoma. However the effect of marijuana on intraocular pressure (IOC) is not as effective as those offered by other drugs on the market.<ref>[http://www.nei.nih.gov/news/statements/marij.asp National Eye Institue: Glaucoma and Marijuana use]</ref>  
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Marijuana is an [[antispasmodic]] and [[anticonvulsant]] is used in the treatment of seizures.<ref>[http://www.nap.edu/openbook.php?record_id=9586&page=106 National Academies Press: Marijuana and muscle spasticity]</ref> Marijuana is also used in the treatment of migraines, arthritis,<ref>[http://onlinelibrary.wiley.com/doi/10.1002/art.1780090304/abstract Online Library: Treatment of adjuvant arthritis in rats with anti-inflammatory drugs]</ref> depression,<ref name="interestingfacts.org">[http://www.interestingfacts.org/fact/facts-about-marijuana Interesting Facts: Facts about marijuana]</ref> and glaucoma. However the effect of marijuana on intraocular pressure (IOC) is not as effective as those offered by other drugs on the market.<ref>[http://www.nei.nih.gov/news/statements/marij.asp National Eye Institue: Glaucoma and Marijuana use]</ref>  
    
There have not been many in-depth and widely distributed studies into the possible medicinal effects of marijuana. However, with pressure from [[liberal]] advocates of marijuana, more otherwise accredited institutions are conducting research on the drug.
 
There have not been many in-depth and widely distributed studies into the possible medicinal effects of marijuana. However, with pressure from [[liberal]] advocates of marijuana, more otherwise accredited institutions are conducting research on the drug.
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"Medicinal" marijuana is used by proper doctors as a last-resort in states where it is legal or semi-legal (with a prescription, honored only by the state), and abused by perfectly healthy people who simply want to get high. "Medicinal" marijuana, however well-intentioned, will obviously lead to abuses in that system.
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Despite state legality, physicians are reluctant to prescribe medicinal marijuana fearing it may jeopardize their DEA license to prescribe controlled substances.<ref>{{Cite web|url=http://www.medscape.com/viewarticle/810356|title=Medical Marijuana: The Imperative of Educating Physicians|last=Schatman|first=Michael|date=September 6, 2013|website=Medscape|archive-url=|archive-date=|dead-url=|access-date=}}</ref> Medicinal marijuana is used by physicians as a last-resort in states where it is legal or semi-legal (under state law), but also misused by people who simply want to get high. Medicinal marijuana, however well-intentioned, will also lead to abuses in that system.
    
==Marinol==
 
==Marinol==
Marinol (medically named Dronabinol) is a Schedule III controlled substance, only prescribed in truly remarkable situations. It is essentially Δ-9-Tetrahydrocannabinol isolated into a capsule in accordance with the Single Convention, very similarly in the manner in which morphine is a controlled substance used as a pain-killer by isolating the active chemicals in the opioid plant. Liberals advocating for "medicinal" marijuana are quickly stifled by the very mention of this drug. It is primarily used as an appetite-stimulant for cancer patients enduring chemotherapy, as well as those diagnosed with terminal AIDS.  Doctors are extremely cautious in prescribing Marinol, due to the potential of lawsuits; as such, healthy people looking for a "legal high" will not get it.
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''Marinol'' (a brand formulation of dronabinol)<ref>{{Cite web|url=http://www.drugscience.org/Archive/bcr3/n3_Marinol.html|title=The Bulletin of Cannabis Reform|website=www.drugscience.org|access-date=2017-02-17}}</ref> is a schedule III controlled substance, approved for relief of nausea and vomiting in persons undergoing cancer chemotherapy and to improve appetite in persons with AIDS. It is dispensed in gelatin capsules containing synthetic Δ-9-Tetrahydrocannabinol dissolved in sesame oil. Liberals advocating for "medicinal" marijuana are quickly stifled by the very mention of this drug. Doctors are extremely cautious in prescribing Marinol{{cn}}, due to the potential of lawsuits; as such, healthy people looking for a "legal high" will not get it. A 1998 survey of physicians, addiction specialists and police demonstrated no evidence or concern about the abuse, dependence or diversion of Marinol.<ref>{{Cite journal|last=Calhoun|first=S. R.|last2=Galloway|first2=G. P.|last3=Smith|first3=D. E.|date=1998-04-01|title=Abuse potential of dronabinol (Marinol)|url=https://www.ncbi.nlm.nih.gov/pubmed/?term=9692381|journal=Journal of Psychoactive Drugs|volume=30|issue=2|pages=187–196|doi=10.1080/02791072.1998.10399689|issn=0279-1072|pmid=9692381}}</ref> About this time, the DEA moved the drug from schedule II to the less restrictive schedule III.<ref>{{Cite web|url=https://www.deadiversion.usdoj.gov/fed_regs/rules/1998/fr1105.htm|title=Proposed Rules - 1998 - Schedules of Controlled Substances: Rescheduling of Synthetic Dronabinol (Martinol®; (-)-Δ9-(trans)-Tetrahydrocannabinol in Sesame oil and Encapsulated in Soft Gelatin Capsules) From Schedule II to Schedule III.|website=www.deadiversion.usdoj.gov|language=en-US|access-date=2017-02-17}}</ref>
    
==Interesting Facts==
 
==Interesting Facts==

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