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Only live attenuated vaccines can still cause infection. All vaccines can cause illness, but this is commonly a hypersensitivity reaction (similar to an allergic response), not due to the disease itself. Very rarely a serious disease known as eczema vaccinatum]can emerge. Vaccines that use pieces of pathogens often use a carrier virus in the injection. Those with very weak immune systems that are exposed to such a vaccine can become infected with the carrier virus and develop [[eczema]]. A recent case of this was reported in the United States after a military man was vaccinated with smallpox and his two-year-old son became ill.<ref>http://www.associatedcontent.com/article/183349/soldier_infects_toddler_son_with_lifethreatening.html AP article on eczema vaccinatum</ref>
 
Only live attenuated vaccines can still cause infection. All vaccines can cause illness, but this is commonly a hypersensitivity reaction (similar to an allergic response), not due to the disease itself. Very rarely a serious disease known as eczema vaccinatum]can emerge. Vaccines that use pieces of pathogens often use a carrier virus in the injection. Those with very weak immune systems that are exposed to such a vaccine can become infected with the carrier virus and develop [[eczema]]. A recent case of this was reported in the United States after a military man was vaccinated with smallpox and his two-year-old son became ill.<ref>http://www.associatedcontent.com/article/183349/soldier_infects_toddler_son_with_lifethreatening.html AP article on eczema vaccinatum</ref>
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A number of vaccination reactions are deemed serious enough to contraindicate further vaccinations of the same type. These include extensive swelling and redness at the injection site, prolonged fever, [[bronchospasm]] and laryngeal [[edema]](narrowing of the airways causing difficulty in breathing), and collapse/seizures with or without unconsciousness and/or encephalitis.<ref>[http://www.gpnotebook.co.uk/simplepage.cfm?ID=2067071044 General Practice Notebook - vaccine reactions]</ref>
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A number of vaccination reactions are deemed serious enough to contraindicate further vaccinations of the same type. These include extensive swelling and redness at the injection site, prolonged fever, bronchospasm and laryngeal [[edema]] (narrowing of the airways causing difficulty in breathing), and collapse/seizures with or without unconsciousness and/or encephalitis.<ref>[http://www.gpnotebook.co.uk/simplepage.cfm?ID=2067071044 General Practice Notebook - vaccine reactions]</ref>
    
===Published Adverse Reaction Rates===
 
===Published Adverse Reaction Rates===
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