'''Sickle cell anemia''' is a serious condition in which the red [[blood]] cells can become sickle-shaped (that is, shaped like a "C").
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Normal red [[blood]] cells are smooth and round like a doughnut without a hole. They move easily through [[blood vessel]]s to carry oxygen to all parts of the body. Sickle-shaped cells don't move easily through blood. They're stiff and sticky and tend to form clumps and get stuck in blood vessels.
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The clumps of sickle cells block blood flow in the blood vessels that lead to the limbs and organs. Blocked blood vessels can cause pain, serious infections, and organ damage.