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|Seasons 1-8: Lead character Charlie Harper (Charlie Sheen) is an [[alcoholism|alcoholic]] jingle writer whose series of casual sexual relationships is admired and envied by others, while his younger brother Alan, a tightly-wound chiropractor who is more moral and hard-working by comparison, is more prone to misfortune. There is a lack of positive female role models, and Charlie has an antagonistic and dysfunctional relationship with his narcissistic, emotionally toxic mother, which is passed off as humorous.
 
|Seasons 1-8: Lead character Charlie Harper (Charlie Sheen) is an [[alcoholism|alcoholic]] jingle writer whose series of casual sexual relationships is admired and envied by others, while his younger brother Alan, a tightly-wound chiropractor who is more moral and hard-working by comparison, is more prone to misfortune. There is a lack of positive female role models, and Charlie has an antagonistic and dysfunctional relationship with his narcissistic, emotionally toxic mother, which is passed off as humorous.
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Seasons 9-12: After saying goodbye to the late Charlie (a response to Sheen's dismissal from further appearances following his real-world bout with alcoholism, drug abuse, and adultery), Alan meets and takes in tech company billionaire Walden Schmidt, whose divorce from his wife is presented positively. One of the episodes depicts Alan's ex-wife and current girlfriend implied to have undergone a lesbian one-night-stand. In another episode, Jake, Alan's son, comments about getting a sexually transmitted disease as if it were a badge of honor.  
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Seasons 9-12: After saying goodbye to the late Charlie (a response to Sheen's dismissal from further appearances following his real-world bout with alcoholism, drug abuse, and adultery), Alan meets and takes in tech company billionaire Walden Schmidt, whose divorce from his wife is presented positively. In one episode, Alan's ex-wife Judith is implied to have undergone a lesbian one-night-stand. In another episode, Alan's son Jake comments about getting a sexually transmitted disease as if it were a badge of honor.  
    
In November 2012, Angus T. Jones, Jake's actor, began speaking out against the show, which he had recently left, and labeled it as filth after his famous conversion to Christianity the previous month.
 
In November 2012, Angus T. Jones, Jake's actor, began speaking out against the show, which he had recently left, and labeled it as filth after his famous conversion to Christianity the previous month.
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