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| | [[Image:Vaccine.jpg|right|thumb|350px|[[Avian flu]] vaccine development]] | | [[Image:Vaccine.jpg|right|thumb|350px|[[Avian flu]] vaccine development]] |
| − | A '''vaccine''' is a pharmaceutical product containing an [[antigen]] designed to stimulate the production of antibodies against a particular disease or diseases.<ref>https://www.sciencenewsforstudents.org/article/explainer-what-vaccine</ref> Vaccination requirements are inserted into laws, often unjustifiably, by [[Big Pharma]] for profits and by governmental officials to increase their control. It is common for advocates of vaccination to receive undisclosed compensation from Big Pharma, either directly or through a spouse. | + | A '''vaccine''' is a pharmaceutical product containing an [[antigen]] designed to stimulate the production of antibodies against a particular disease or diseases.<ref>https://www.sciencenewsforstudents.org/article/explainer-what-vaccine</ref> While this sounds like a beneficial thing in theory, there is significant controversy on this topic. There are numerous reasons why some people prefer to avoid taking vaccines, but laws and other rules (often pushed into place by those who stand to make significant profit) frequently mandate them. |
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| − | Many injuries from vaccination are admitted by the government, and severe potential side effects are disclosed on packaging labels that most parents never see. The sharp rise in [[autism]], which is generally considered incurable and afflicts 1 out of every 59 children, has a correlation with the increase in vaccination; the incidence of autism is greater in states where children receive more vaccines, such as [[New Jersey]] and [[North Carolina]].<ref>https://www.healthline.com/health/autism/autism-rates-by-state#2</ref> "The new estimate represents a 15% increase from two years prior and a 150% increase since 2000."<ref>https://www.cnn.com/2018/04/26/health/autism-prevalence-cdc/index.html</ref> ''See generally'' [[vaccines and autism]].
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| − | Traditionally a few highly tested vaccines were recommended for children to protect against deadly or severe diseases, such as [[smallpox]] and [[polio]]. Beginning in the 1990s, however, profit-driven vaccine manufacturers lobbied states and pediatrician organizations to compel numerous additional vaccines for sexually transmitted or less dangerous diseases. In addition, emotion based on inadequate information can cause over-vaccination.
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| − | 17 US states have philosophical exemptions allowing parents to decline the vaccines; 47 states have religious exemptions; all states have medical exemptions,<ref>https://www.nvic.org/Vaccine-Laws/state-vaccine-requirements.aspx</ref><ref>http://www.vaccinesafety.edu/cc-exem.htm</ref> but they are hardest to obtain. Some parents choose to [[homeschooling|homeschool]] rather than submit their children to numerous vaccinations as required by state laws, due to lobbying by vaccine manufacturers, as a condition of being in school.
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| | ==Mechanism== | | ==Mechanism== |
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| | If the body produces an antibody against a particular disease or toxin it can identify the infection early on and the [[immune system]] can destroy it. Vaccines work by exposing the body to a form of the disease in such a way that it is much less likely to cause illness but still allows antibodies to develop. This confers a level of immunity to the person or animal vaccinated.<ref>http://www.howstuffworks.com/immune-system7.htm How stuff works: Antibodies</ref> | | If the body produces an antibody against a particular disease or toxin it can identify the infection early on and the [[immune system]] can destroy it. Vaccines work by exposing the body to a form of the disease in such a way that it is much less likely to cause illness but still allows antibodies to develop. This confers a level of immunity to the person or animal vaccinated.<ref>http://www.howstuffworks.com/immune-system7.htm How stuff works: Antibodies</ref> |
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| | ==Influenza Vaccine== | | ==Influenza Vaccine== |
| − | | + | The flu vaccine is an example of modern vaccination. Due to the change in [[allele]] frequency over time in the population of the influenza virus, new influenza vaccines are created each year. In some years the vaccines are less effective than in other years. According to the CDC,<ref>"Inactivated Influenza Vaccine, What you need to know," a publication of the Center for Disease Control, 2006. Available online at: https://www.cdc.gov/nip/publications/VIS/vis-flu.pdf</ref> |
| − | The flu vaccine is an example of modern vaccination. Due to the change in [[allele]] frequency over time in the population of the influenza virus, new influenza vaccines are created each year. In some years the vaccines are less effective than in other years. According to the [https://www.cdc.gov/ CDC],<ref>"Inactivated Influenza Vaccine, What you need to know," a publication of the Center for Disease Control, 2006. Available online at: https://www.cdc.gov/nip/publications/VIS/vis-flu.pdf</ref> | |
| | <blockquote> | | <blockquote> |
| | Influenza viruses are always changing. Therefore, influenza vaccines are updated every year, and annual vaccination is recommended. | | Influenza viruses are always changing. Therefore, influenza vaccines are updated every year, and annual vaccination is recommended. |
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| | Since the production of the vaccine must begin many months before the influenza season starts models of the population genetics of the virus must be produced.<ref>http://www.nature.com/nrd/journal/v5/n3/full/nrd1988.html Influenza vaccines</ref> The success of vaccinations programs is dependent on the accuracy of these predictions.<ref>http://www.nature.com/news/2003/030324/full/030324-5.html Flu changes modeled</ref> The National Institute of Health recently assigned $26 million to establish a research center to better develop molecular models of influenza.<ref>http://www.spiritindia.com/health-care-news-articles-8024.html $26 million NIH contract to establish new flu/bird flu Center of Excellence</ref> | | Since the production of the vaccine must begin many months before the influenza season starts models of the population genetics of the virus must be produced.<ref>http://www.nature.com/nrd/journal/v5/n3/full/nrd1988.html Influenza vaccines</ref> The success of vaccinations programs is dependent on the accuracy of these predictions.<ref>http://www.nature.com/news/2003/030324/full/030324-5.html Flu changes modeled</ref> The National Institute of Health recently assigned $26 million to establish a research center to better develop molecular models of influenza.<ref>http://www.spiritindia.com/health-care-news-articles-8024.html $26 million NIH contract to establish new flu/bird flu Center of Excellence</ref> |
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| − | ==Herd immunity and mandatory vaccination== | + | ==Problems== |
| − | When a certain percentage of a population is vaccinated, those within the population who are not vaccinated are protected from the disease, this is called [[herd immunity]]. If 90 percent of a population is immune, then the chances that a carrier of the disease will come into contact with a non-immune member of the population (or "herd") is low.<ref>http://www.mathepi.com/maindir/herd.html The mathematics of herd immunity</ref> Herd immunity is the goal of most vaccination programs as it is the point where disease can start to be eliminated from a population altogether.
| + | Vaccination requirements are inserted into laws, often unjustifiably, by [[Big Pharma]] for profits and by governmental officials to increase their control. It is common for advocates of vaccination to receive undisclosed compensation from Big Pharma, either directly or through a spouse. This medial offering which was initially developed and released as something to benefit society has become a point of tension and even oppression to many individuals. |
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| − | For example, in 1962 Japan instituted mandatory vaccination against influenza in school children. This continued until 1987 when the program was changed to optional; it was abandoned in 1994. Approximately 85 percent of children were estimated to have been vaccinated.<ref>{{hnb|Glezen|2004}}</ref> Several studies examined the mortality rates due to influenza during this period of time and revealed that the death rates due to influenza in all population groups were drastically decreased, including older adult populations. Since there was no increased rate of vaccination in these populations, the decreased mortality was caused by herd immunity effects of vaccinating so many children.<ref>http://www.newsrx.com/newsletters/Vaccine-Weekly/2001-04-11/200104113335VW.html Mandatory Vaccination of Japanese Schoolchildren Demonstrates "Herd Immunity"</ref> Many researchers have written that this and other evidence argues strongly for mandatory vaccination programs worldwide as a means of controlling many diseases and preventing a [[pandemic]].<ref>http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1360502 Herd Immunity</ref>
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| − | The USA has federal vaccination recommendations according to an official CDC schedule. Requirements are up to the states. Most states have medical and religious exemptions. Some states make it very easy to opt-out of vaccines, while other states strictly enforce compliance for school attendance. The difference in vaccination rates between these states is actually very slight, and usually not nearly enough to affect herd immunity.{{cn}}
| + | Many injuries from vaccination are admitted by the government, and severe potential side effects are disclosed on packaging labels that most parents never see. The sharp rise in [[autism]], which is generally considered incurable and afflicts 1 out of every 59 children, has a correlation with the increase in vaccination; the incidence of autism is greater in states where children receive more vaccines, such as [[New Jersey]] and [[North Carolina]].<ref>https://www.healthline.com/health/autism/autism-rates-by-state#2</ref> "The new estimate represents a 15% increase from two years prior and a 150% increase since 2000."<ref>https://www.cnn.com/2018/04/26/health/autism-prevalence-cdc/index.html</ref> ''See generally'' [[vaccines and autism]]. |
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| − | As of February 2008, the CDC noted that "fewer than 100 measles cases are now reported annually in the United States and virtually all of those are linked to imported cases" in which someone is infected during overseas travel. The USA maintains herd immunity for measles, even in states where it is easy to opt-out of vaccination requirements.<ref>[https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref> Measles can be serious; according to an article in The Times, "About one in every 15 children has complications that can include [[meningitis]], [[pneumonia]], [[fits]], [[encephalitis]] (swelling of the brain), [[blindness]] and [[brain damage]]."<ref>The Sunday Times, ''How the MMR scare led to the return of measles'', February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683687.ece]</ref> In the England and Wales, there were 1,348 cases of measles in 2008; two children died of the disease.<ref>The Sunday Times, ''MMR doctor Andrew Wakefield fixed data on autism'', by Brian Deer, February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece]</ref>
| + | Traditionally a few highly tested vaccines were recommended for children to protect against deadly or severe diseases, such as [[smallpox]] and [[polio]]. Beginning in the 1990s, however, profit-driven vaccine manufacturers lobbied states and pediatrician organizations to compel numerous additional vaccines for sexually transmitted or less dangerous diseases. In addition, emotion based on inadequate information can cause over-vaccination. |
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| − | The CDC notes that when a measles outbreak occurs, the cost to taxpayers can be substantial. Public health responsibilities include "identification of cases, isolation of patients and vaccination, administration of [[immune globulin]], and voluntary quarantine of contacts who have no evidence of measles immunity...In Iowa, the public health response to one imported measles case cost approximately $150,000."<ref>Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, ''Outbreak of Measles --- San Diego, California, January--February 2008'', February 29, 2008 [https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref>
| + | 17 US states have philosophical exemptions allowing parents to decline the vaccines; 47 states have religious exemptions; all states have medical exemptions,<ref>https://www.nvic.org/Vaccine-Laws/state-vaccine-requirements.aspx</ref><ref>http://www.vaccinesafety.edu/cc-exem.htm</ref> but they are hardest to obtain. Some parents choose to [[homeschooling|homeschool]] rather than submit their children to numerous vaccinations as required by state laws, due to lobbying by vaccine manufacturers, as a condition of being in school. |
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| − | Other diseases besides the measles have also started not only to reappear but also to kill children. Hib (''[[Haemophilus influenzae]]'' type B) meningitis recently killed an infant in Minnesota. The child who died had not been vaccinated. Two others who had been either partially, but not fully, vaccinated, or who had an immune deficiency became seriously ill. The vaccine for Hib is less than twenty years old, but this is the first death due to the disease in the state of Minnesota since the vaccine was introduced.<ref>[http://children.webmd.com/vaccines/news/20090123/hib-outbreak-kills-unvaccinated-child Hib Outbreak Kills Unvaccinated Child]</ref>
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| − | ===Herd Immunity in Britain=== | + | === Adverse Reactions === |
| − | Due to a decrease in vaccination, measles has become endemic in Britain. This means that measles does not need to be brought in by travelers, but instead has a large enough base of non-immune individuals for it to continuously spread inside the country. In London, only 71 percent of children receive the first dose of the vaccine and only 51 percent receive the second dose. Due to this decline, there were 461 measles cases in Britain in the first half of 2008. These cases have had tragic consequences, with the death of a 17-year-old reported in 2008.<ref>[http://www.healthdirect.co.uk/2008/07/measles-endemic-in-britain-official.html Health Direct NHS watch blog]</ref> This immunization failure is due to parents opting out of the MMR vaccine program in the wake of the false claims that the MMR vaccine causes autism.<ref>https://www.thetimes.co.uk/article/no-doubt-the-mmr-vaccine-does-not-cause-autism-zpxk37ntzmh</ref>
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| − | == Adverse Reactions == | |
| | {{See also|Vaccine Injury Compensation Program|Vaccine Adverse Event Reporting System}} | | {{See also|Vaccine Injury Compensation Program|Vaccine Adverse Event Reporting System}} |
| | Vaccines have substantial side effects, and many vaccines have significant morbidity and mortality associated with them. In the fiscal year 2017 alone, it is estimated that $220 million will be paid to victims of vaccines, and underpayments or improper denials of payment are common.<ref>http://www.wakingtimes.com/2017/05/09/whopping-vaccine-injury-payouts-us-fiscal-year-2017-released/</ref> More than Postvaccinial encephalitis is a known hazard of [[smallpox]] vaccine, for example. A recently introduced vaccine against human papilloma virus, the causative agent of cancer of the [[uterus|uterine]] cervix, has now been linked to a number of sudden deaths reported within days of its administration.<ref name=GardasilMM>Cockcroft, Lucy, "[https://www.telegraph.co.uk/news/main.jhtml?xml=/news/2007/10/29/njab129.xml Cervical cancer drug Gardasil linked to deaths]," ''[[London]] Daily Telegraph'', October 29, 2007. Retrieved November 10, 2007.</ref> | | Vaccines have substantial side effects, and many vaccines have significant morbidity and mortality associated with them. In the fiscal year 2017 alone, it is estimated that $220 million will be paid to victims of vaccines, and underpayments or improper denials of payment are common.<ref>http://www.wakingtimes.com/2017/05/09/whopping-vaccine-injury-payouts-us-fiscal-year-2017-released/</ref> More than Postvaccinial encephalitis is a known hazard of [[smallpox]] vaccine, for example. A recently introduced vaccine against human papilloma virus, the causative agent of cancer of the [[uterus|uterine]] cervix, has now been linked to a number of sudden deaths reported within days of its administration.<ref name=GardasilMM>Cockcroft, Lucy, "[https://www.telegraph.co.uk/news/main.jhtml?xml=/news/2007/10/29/njab129.xml Cervical cancer drug Gardasil linked to deaths]," ''[[London]] Daily Telegraph'', October 29, 2007. Retrieved November 10, 2007.</ref> |
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| | *The MMR vaccine has a .00484% chance of causing [[thrombocytopenia]]. However, the measles and rubella both have much higher chances of causing thrombocytopenia.<ref>[http://adc.bmj.com/cgi/content/full/84/3/227 E Miller et al., Idiopathic thrombocytopenic purpura and MMR vaccine in ''Archives of Disease In Childhood'', 84:227-229]</ref> | | *The MMR vaccine has a .00484% chance of causing [[thrombocytopenia]]. However, the measles and rubella both have much higher chances of causing thrombocytopenia.<ref>[http://adc.bmj.com/cgi/content/full/84/3/227 E Miller et al., Idiopathic thrombocytopenic purpura and MMR vaccine in ''Archives of Disease In Childhood'', 84:227-229]</ref> |
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| − | == Common Misconceptions Surrounding Vaccines == | + | === Common Misconceptions Surrounding Vaccines === |
| | Many people assume that official vaccine recommendations are based on recommendations of independent panels of experts after reviewing risk-benefit and cost-benefit analyses. They are not. The government panels are dominated by vaccine industry representatives and they have no consumer representatives.{{cn}} | | Many people assume that official vaccine recommendations are based on recommendations of independent panels of experts after reviewing risk-benefit and cost-benefit analyses. They are not. The government panels are dominated by vaccine industry representatives and they have no consumer representatives.{{cn}} |
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| | Vaccines have injured many in the developing world, sometimes due to contamination in donated stale vaccines. The vaccine was banned for over a year in Nigeria after concerns about safety were raised. The ban has since been lifted, but the vaccination rate remains low.{{cn}} | | Vaccines have injured many in the developing world, sometimes due to contamination in donated stale vaccines. The vaccine was banned for over a year in Nigeria after concerns about safety were raised. The ban has since been lifted, but the vaccination rate remains low.{{cn}} |
| | + | |
| | + | ==Herd immunity and mandatory vaccination== |
| | + | When a certain percentage of a population is vaccinated, those within the population who are not vaccinated are protected from the disease, this is called [[herd immunity]]. If 90 percent of a population is immune, then the chances that a carrier of the disease will come into contact with a non-immune member of the population (or "herd") is low.<ref>http://www.mathepi.com/maindir/herd.html The mathematics of herd immunity</ref> Herd immunity is the goal of most vaccination programs as it is the point where disease can start to be eliminated from a population altogether. |
| | + | |
| | + | For example, in 1962 Japan instituted mandatory vaccination against influenza in school children. This continued until 1987 when the program was changed to optional; it was abandoned in 1994. Approximately 85 percent of children were estimated to have been vaccinated.<ref>{{hnb|Glezen|2004}}</ref> Several studies examined the mortality rates due to influenza during this period of time and revealed that the death rates due to influenza in all population groups were drastically decreased, including older adult populations. Since there was no increased rate of vaccination in these populations, the decreased mortality was caused by herd immunity effects of vaccinating so many children.<ref>http://www.newsrx.com/newsletters/Vaccine-Weekly/2001-04-11/200104113335VW.html Mandatory Vaccination of Japanese Schoolchildren Demonstrates "Herd Immunity"</ref> Many researchers have written that this and other evidence argues strongly for mandatory vaccination programs worldwide as a means of controlling many diseases and preventing a [[pandemic]].<ref>http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1360502 Herd Immunity</ref> |
| | + | |
| | + | The USA has federal vaccination recommendations according to an official CDC schedule. Requirements are up to the states. Most states have medical and religious exemptions. Some states make it very easy to opt-out of vaccines, while other states strictly enforce compliance for school attendance. The difference in vaccination rates between these states is actually very slight, and usually not nearly enough to affect herd immunity.{{cn}} |
| | + | |
| | + | As of February 2008, the CDC noted that "fewer than 100 measles cases are now reported annually in the United States and virtually all of those are linked to imported cases" in which someone is infected during overseas travel. The USA maintains herd immunity for measles, even in states where it is easy to opt-out of vaccination requirements.<ref>[https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref> Measles can be serious; according to an article in The Times, "About one in every 15 children has complications that can include [[meningitis]], [[pneumonia]], [[fits]], [[encephalitis]] (swelling of the brain), [[blindness]] and [[brain damage]]."<ref>The Sunday Times, ''How the MMR scare led to the return of measles'', February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683687.ece]</ref> In the England and Wales, there were 1,348 cases of measles in 2008; two children died of the disease.<ref>The Sunday Times, ''MMR doctor Andrew Wakefield fixed data on autism'', by Brian Deer, February 8, 2009 [http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece]</ref> |
| | + | |
| | + | The CDC notes that when a measles outbreak occurs, the cost to taxpayers can be substantial. Public health responsibilities include "identification of cases, isolation of patients and vaccination, administration of [[immune globulin]], and voluntary quarantine of contacts who have no evidence of measles immunity...In Iowa, the public health response to one imported measles case cost approximately $150,000."<ref>Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, ''Outbreak of Measles --- San Diego, California, January--February 2008'', February 29, 2008 [https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5708a3.htm]</ref> |
| | + | |
| | + | Other diseases besides the measles have also started not only to reappear but also to kill children. Hib (''[[Haemophilus influenzae]]'' type B) meningitis recently killed an infant in Minnesota. The child who died had not been vaccinated. Two others who had been either partially, but not fully, vaccinated, or who had an immune deficiency became seriously ill. The vaccine for Hib is less than twenty years old, but this is the first death due to the disease in the state of Minnesota since the vaccine was introduced.<ref>[http://children.webmd.com/vaccines/news/20090123/hib-outbreak-kills-unvaccinated-child Hib Outbreak Kills Unvaccinated Child]</ref> |
| | + | |
| | + | ===Herd Immunity in Britain=== |
| | + | Due to a decrease in vaccination, measles has become endemic in Britain. This means that measles does not need to be brought in by travelers, but instead has a large enough base of non-immune individuals for it to continuously spread inside the country. In London, only 71 percent of children receive the first dose of the vaccine and only 51 percent receive the second dose. Due to this decline, there were 461 measles cases in Britain in the first half of 2008. These cases have had tragic consequences, with the death of a 17-year-old reported in 2008.<ref>[http://www.healthdirect.co.uk/2008/07/measles-endemic-in-britain-official.html Health Direct NHS watch blog]</ref> This immunization failure is due to parents opting out of the MMR vaccine program in the wake of the false claims that the MMR vaccine causes autism.<ref>https://www.thetimes.co.uk/article/no-doubt-the-mmr-vaccine-does-not-cause-autism-zpxk37ntzmh</ref> |
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| | ==References== | | ==References== |
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| | == See also == | | == See also == |
| − | *[[Vaccines and autism]]
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| | *[[HPV vaccine]] | | *[[HPV vaccine]] |
| | *[[Vaccine Injury Compensation Program]] | | *[[Vaccine Injury Compensation Program]] |