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Saint was born in the small town of Franklin, the seat of government of St. Mary Parish in south Louisiana to John Davidson Saint and the former Ellen Jane DuBose, both natives of [[Alabama]]. He was educated in local private schools and attended the [[University of Alabama]] at [[Tuscaloosa, Alabama|Tuscaloosa]] from 1888 to 1890. He subsequently graduated in 1893 from [[Tulane University]] Law School in [[New Orleans]].<ref name=lahist/>​

Saint was born in the small town of Franklin, the seat of government of St. Mary Parish in south Louisiana to John Davidson Saint and the former Ellen Jane DuBose, both natives of [[Alabama]]. He was educated in local private schools and attended the [[University of Alabama]] at [[Tuscaloosa, Alabama|Tuscaloosa]] from 1888 to 1890. He subsequently graduated in 1893 from [[Tulane University]] Law School in [[New Orleans]].<ref name=lahist/>​

From a first marriage to the former Mary Isabel Thorp on April 12, 1898, there were no children. On December 7, 1903, he married the former Cora Lee McCardell, daughter of the former Lavinia Pelichet and Thomas McCardell. The couple had a son, Percy DuBose Saint (1908-1974),<ref>It is unclear whether the son was Percy, Jr., or if Percy Saint's middle name was DuBose or some3 other name starting with a "D."</ref> and a daughter, Mary Isabel. In 1893, Saint was admitted to the bar and served two years as a messenger in the [[United States Congress]]. He began his law practice in his native Franklin, where he edited ''The  Franklin Vindicator News'' from 1898 until 1900.<ref name=lahist/>

From a first marriage to the former Mary Isabel Thorp on April 12, 1898, there were no children. On December 7, 1903, he married the former Cora Lee McCardell, daughter of the former Lavinia Pelichet and Thomas McCardell. The couple had a son, Percy DuBose Saint (1908-1974),<ref>It is unclear whether the son was Percy, Jr., or if Percy Saint's middle name was DuBose or some other name starting with a "D."</ref> and a daughter, Mary Isabel. In 1893, Saint was admitted to the bar and served two years as a messenger in the [[United States Congress]]. He began his law practice in his native Franklin, where he edited ''The  Franklin Vindicator News'' from 1898 until 1900.<ref name=lahist/>

The Saint House at 303 Main Street in Franklin was built in 1908. On the historic house tour of Franklin, the Saint House is styled in the manner of the Woodcraft movement with columns shingled with overlapping weatherboard. The front gable pediment has a wattle and daub treatment.<ref>{{cite web|url=http://www.franklin-la.org/recreation-walkingtours.php|title=Recreation & Visitor Info|publisher=franklin-la.org|accessdate=April 16, 2011}}</ref>​

The Saint House at 303 Main Street in Franklin was built in 1908. On the historic house tour of Franklin, the Saint House is styled in the manner of the Woodcraft movement with columns shingled with overlapping weatherboard. The front gable pediment has a wattle and daub treatment.<ref>{{cite web|url=http://www.franklin-la.org/recreation-walkingtours.php|title=Recreation & Visitor Info|publisher=franklin-la.org|accessdate=April 16, 2011}}</ref>​