Poplar Bluff is an important regional hub, due to the major highways which pass through it as well as its position between the "Bootheel" and the Ozark Plateau. It is often nicknamed "The Gateway to the Ozarks." | Poplar Bluff is an important regional hub, due to the major highways which pass through it as well as its position between the "Bootheel" and the Ozark Plateau. It is often nicknamed "The Gateway to the Ozarks." |