'''Pemiscot County''' is a county in the "Bootheel" region of southeastern [[Missouri]], organized in 1851. It had a population of 18,296 at the 2010 census. The name derives from the local Pemiscot Bayou and is thought to come from the Fox tribe's ''pem-eskaw'', or "liquid mud." [[Caruthersville, Missouri|Caruthersville]] is the county seat and largest city. | '''Pemiscot County''' is a county in the "Bootheel" region of southeastern [[Missouri]], organized in 1851. It had a population of 18,296 at the 2010 census. The name derives from the local Pemiscot Bayou and is thought to come from the Fox tribe's ''pem-eskaw'', or "liquid mud." [[Caruthersville, Missouri|Caruthersville]] is the county seat and largest city. |