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| − | '''Coronavirus treatments''' are being discussed without any proof yet of effectiveness. | + | '''Coronavirus treatments''' are being discussed without any conclusive proof yet of effectiveness. |
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| | The [[FDA]] sharply impedes the development of new medications in the [[United States]], while [[communist]] [[China]] allows more freedom in rapidly developing and using new treatments. But the FDA is not authorized to make decisions about the practice of medicine, and thus it is generally allowed for a physician to use an old medication for a new purpose if it has been previously approved without limitation by the FDA. This is known as "off-label" use of a drug. | | The [[FDA]] sharply impedes the development of new medications in the [[United States]], while [[communist]] [[China]] allows more freedom in rapidly developing and using new treatments. But the FDA is not authorized to make decisions about the practice of medicine, and thus it is generally allowed for a physician to use an old medication for a new purpose if it has been previously approved without limitation by the FDA. This is known as "off-label" use of a drug. |
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| | As explained by the website for the [[National Institutes of Health]]:<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538391/</ref> | | As explained by the website for the [[National Institutes of Health]]:<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538391/</ref> |
| | {{cquote|Off-label drug use involves prescribing medications for indications, or using a dosage or dosage form, that have not been approved by the US Food and Drug Administration. Since the Food and Drug Administration does not regulate the practice of medicine, OLDU has become common. It occurs in every specialty of medicine ....}} | | {{cquote|Off-label drug use involves prescribing medications for indications, or using a dosage or dosage form, that have not been approved by the US Food and Drug Administration. Since the Food and Drug Administration does not regulate the practice of medicine, OLDU has become common. It occurs in every specialty of medicine ....}} |
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| | + | French researchers using a small sample size found a high cure rate by using a combination of hydroxychloroquine (a treatment for malaria and azithromycin (an antibiotic):<ref>Gautret et al. (2020) Hydroxychloroquine and azithromycin as a treatment of |
| | + | COVID‐19: results of an open‐label non‐randomized clinical trial. International Journal of |
| | + | Antimicrobial Agents – In Press 17 March 2020 – DOI : 10.1016/j.ijantimicag.2020.105949 [https://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA.pdf]</ref> |
| | + | {{Cquote|Six patients were asymptomatic, 22 had upper respiratory tract infection symptoms and eight had lower respiratory tract infection symptoms. |
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| | + | Twenty cases were treated in this study and showed a significant reduction of the viral carriage at D6-post inclusion compared to controls, and much lower average carrying duration than reported of untreated patients in the literature. Azithromycin added to hydroxychloroquine was significantly more efficient for virus elimination.}} |
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| | An article in ''Nature'' suggests the potential for off-label use of hydroxychloroquine, which was used long ago for [[malaria]] and was first synthesized in 1946, to treat [[coronavirus]] (SARS-CoV-2):<ref name="Nature">https://www.nature.com/articles/s41421-020-0156-0</ref> | | An article in ''Nature'' suggests the potential for off-label use of hydroxychloroquine, which was used long ago for [[malaria]] and was first synthesized in 1946, to treat [[coronavirus]] (SARS-CoV-2):<ref name="Nature">https://www.nature.com/articles/s41421-020-0156-0</ref> |